C1413
Complement C7 deficient serum human
for complement assays
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
UNSPSC kód:
12352202
NACRES:
NA.61
Javasolt termékek
Alkalmazás
Complement C7 deficiencies in humans are rare, but often associated with recurrent infections by Neisseria spp. (such as meningitis). C7 deficiencies in patients with meningococcal meningitis have shown a mutation which results in an 11 bp deletion in exon 6 resulting in a premature stop codon. Additionally, research has suggested that screening of patients with systemic neisserial infection by CH50 or the APH-50 assay can reveal a C7 deficiency.
Fizikai forma
Supplied as a solution in PBS, pH 7.4
Analízis megjegyzés
C7 is depleted by immunoadsorption as judged by a highly sensitive hemolytic assay.
Jogi nyilatkozat
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Tárolási osztály kódja
10 - Combustible liquids
WGK
WGK 3
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
Már rendelkezik ezzel a termékkel?
Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.
Sonia Barroso et al.
Immunology, 118(2), 257-260 (2006-06-15)
Different genetic mutations have been described in complement components resulting in total or subtotal deficiency states. In this work we report the genetic basis of C7 deficiency in a previously reported Spanish patient exhibiting a combined total deficiency of C7
Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction.
S??lzen, et al.
Nature Communications, 14, 2403-2403 (2023)
W P Kolb et al.
Journal of immunology (Baltimore, Md. : 1950), 122(5), 2103-2111 (1979-05-01)
C1q, a subcomponent of the first component of complement, has been isolated from human serum in fully hemolytically active form by affinity column chromatography and gel filtration with Bio-Gel A-5M. The affinity column was prepared by covalent coupling of purified
Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.
Lépjen kapcsolatba a szaktanácsadással