PHR2888

Nitazoxanide

pharmaceutical secondary standard, certified reference material

• Szinonimák: Nitazoxanide, NTZ; 2-(Acetyloxy)-N-(5-nitro-2-thiazolyl)benzamide
• Tapasztalati képlet (Hill-képlet): C₁₂H₉N₃O₅S
• CAS-szám: 55981-09-4
• Molekulatömeg: 307.28
• MDL-szám: MFCD00416599
• UNSPSC kód: 41116107
• NACRES: NA.24

Tulajdonságok

• grade: certified reference material; pharmaceutical secondary standard
• Minőségi szint: 300
• Ügynökség: traceable to USP 1463960
• API-család: nitazoxanide
• Analitikai műbizonylat: current certificate can be downloaded
• kiszerelés: pkg of 400 mg
• alkalmazás(ok): pharmaceutical
• tárolási hőmérséklet: 2-8°C
• SMILES string: CC(=O)Oc1ccccc1C(=O)Nc2ncc(s2)[N+]([O-])=O
• InChI: 1S/C12H9N3O5S/c1-7(16)20-9-5-3-2-4-8(9)11(17)14-12-13-6-10(21-12)15(18)19/h2-6H,1H3,(H,13,14,17)
• Nemzetközi kémiai azonosító kulcs: YQNQNVDNTFHQSW-UHFFFAOYSA-N

Leírás

Általános leírás

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Alkalmazás

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biokémiai/fiziológiai hatások

Nitazoxanide is an inhibitor of pyruvate-ferredoxin oxidoreductase (PFOR); FDA approved anti-parasitic drug (2002). Recent work (C & EN Sept. 14, 2009, p. 28) highlights that NTZ kills non-replicating and replicating TB bacteria and no apparent resistance is detected.

Analízis megjegyzés

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Egyéb megjegyzések

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable