PHR1276

Niacin (Nicotinic Acid)

Pharmaceutical Secondary Standard; Certified Reference Material

• Szinonimák: Nicotinic acid, 3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B₃
• Tapasztalati képlet (Hill-képlet): C₆H₅NO₂
• CAS-szám: 59-67-6
• Molekulatömeg: 123.11
• Beilstein: 109591
• EC-szám: 200-441-0
• MDL-szám: MFCD00006391
• UNSPSC kód: 41116107
• PubChem Substance ID: 329823272
• NACRES: NA.24

Tulajdonságok

• grade: certified reference material; pharmaceutical secondary standard
• Minőségi szint: 300
• Ügynökség: traceable to Ph. Eur. N0700000; traceable to USP 1461003
• API-család: nicotinic acid
• Analitikai műbizonylat: current certificate can be downloaded
• technika/technikák: HPLC: suitable; gas chromatography (GC): suitable
• mp: 236-239 °C (lit.)
• alkalmazás(ok): pharmaceutical (small molecule)
• Formátum: neat
• tárolási hőmérséklet: 2-30°C
• SMILES string: OC(=O)c1cccnc1
• InChI: 1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
• Nemzetközi kémiai azonosító kulcs: PVNIIMVLHYAWGP-UHFFFAOYSA-N

Leírás

Általános leírás

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Niacin (Nicotinic Acid) is commonly used as a dietary supplement, and its deficiency can cause pellagra. It is involved in the synthesis of coenzymes such as NAD and NADP, which are quite essential for enzymatic reactions.
As a lipid-lowering agent, it helps in the prevention of coronary heart disease, carotid artery disease and other atherosclerotic vascular diseases.

Alkalmazás

Niacin (Nicotinic Acid) may be used as a secondary pharma standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique and reversed-phase high-performance liquid chromatography technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analízis megjegyzés

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Egyéb megjegyzések

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Lábjegyzet

To see an example of a Certificate of Analysis for this material enter LRAB7604 in the slot below. This is an example certificate only and may not be the lot that you receive.

Javasolt termékek

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Biztonsági adatok

• Piktogramok: GHS07
• Figyelmeztetés: Warning
• Figyelmeztető mondatok: H319
• Óvintézkedésre vonatkozó mondatok: P280 - P305 + P351 + P338 - P337 + P313
• Veszélyességi osztályok: Eye Irrit. 2
• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): 379.4 °F - closed cup
• Lobbanási pont (C): 193 °C - closed cup