32211-M

Chloroform

puriss. p.a., reag. ISO, reag. Ph. Eur., 99.0-99.4% (GC)

• Szinonimák: Methylidyne trichloride, Trichloromethane
• Tapasztalati képlet (Hill-képlet): CHCl₃
• CAS-szám: 67-66-3
• Molekulatömeg: 119.38
• Beilstein: 1731042
• EC-szám: 200-663-8
• MDL-szám: MFCD00000826
• UNSPSC kód: 12191502
• PubChem Substance ID: 329754102
• NACRES: NA.21

Tulajdonságok

• Ügynökség: USP/NF; reag. ISO; reag. Ph. Eur.
• gőzsűrűség: 4.1 (vs air)
• gőznyomás: 160 mmHg ( 20 °C)
• grade: puriss. p.a.
• Teszt: 99.0-99.4% (GC)
• form: liquid
• tartalmaz: ~1% ethanol as stabilizer
• technika/technikák: RNA extraction: suitable
• szennyeződések: ≤0.00001% free chlorine (Cl); ≤0.00005% free acid (as HCl); ≤0.0005% non-volatile matter; ≤0.005% aldehydes and ketones (as CH₃COCH₃); ≤0.005% carbonyl compounds (as CO); ≤0.01% tetrachloroethene (GC); ≤0.01% tetrachloromethane (GC); ≤0.01% trichloroethene (GC); ≤0.01% water (Karl Fischer); ≤0.03% dichloromethane (GC); 0.6-1.0% ethanol (GC)
• törésmutató: n20/D 1.445 (lit.)
• bp: 60.5-61.5 °C (lit.)
• mp: −63 °C (lit.)
• sűrűség: 1.476-1.483 g/mL at 20 °C; 1.492 g/mL at 25 °C (lit.)
• anion nyomok: chloride (Cl^-): ≤0.0001%
• kation nyomok: Al: ≤0.50 ppm; B: ≤0.02 ppm; Ba: ≤0.10 ppm; Ca: ≤0.50 ppm; Cd: ≤0.05 ppm; Co: ≤0.02 ppm; Cr: ≤0.02 ppm; Cu: ≤0.02 ppm; Fe: ≤0.10 ppm; Mg: ≤0.10 ppm; Mn: ≤0.02 ppm; Ni: ≤0.02 ppm; Pb: ≤0.05 ppm; Sn: ≤0.10 ppm; Zn: ≤0.10 ppm
• SMILES string: ClC(Cl)Cl
• alkalmasság: complies for appearance; complies for reaction against H₂SO₄; complies for suitability of determ. w. dithizone
• InChI: 1S/CHCl3/c2-1(3)4/h1H
• Nemzetközi kémiai azonosító kulcs: HEDRZPFGACZZDS-UHFFFAOYSA-N

Leírás

Általános leírás

Chloroform, a halogenated hydrocarbon, is widely employed as a solvent. Its photochemical degradation has been investigated in the presence of TiO₂ aqueous suspensions (wavelength range of 310-380nm).

Alkalmazás

Chloroform may be employed as a solvent for the following studies:

• Extraction of RNA from plant cells.
• Preparation of dioleoylphosphatidylcholine (DOPC) solution.
• Dissolution of 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC).

It may be employed in a rapid quantitative method for the release of periplasmic proteins from bacterial strains.

Chloroform may be used as a solvent to enhance the enantioselectivity of secondary alcohols formed by the borohydride reduction of carbonyl compounds in the presence of optically active ketoiminatocobalt complexes.

Egyéb megjegyzések

For information on chloroform miscibility, please visit the following link:
Chloroform Miscibility/Immiscibility Table

Biztonsági adatok

• Piktogramok: GHS06,GHS08
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H302,H315,H319,H331,H336,H351,H361d,H372
• Óvintézkedésre vonatkozó mondatok: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Veszélyességi osztályok: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Célzott szervek: Central nervous system, Liver,Kidney
• Tárolási osztály kódja: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Lobbanási pont (F): does not flash
• Lobbanási pont (C): does not flash