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Merck
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Fontos dokumentumok

MAB201

Sigma-Aldrich

Mouse Anti-Rabbit light chain Antibody

Chemicon®, from mouse

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.46

biológiai forrás

mouse

Minőségi szint

konjugátum

unconjugated

antitest forma

ascites fluid

klón

monoclonal

faj reaktivitás

rabbit

gyártó/kereskedő neve

Chemicon®

technika/technikák

ELISA: suitable
western blot: suitable

izotípus

IgG1κ

kiszállítva

wet ice

célzott transzláció utáni módosítás

unmodified

Általános leírás

Antibody molecules typically comprise two immunoglobulin light chains covalently bound to a pair of heavy chains. Immunoglobulin light chains occur in two types, designated by the Greek letters kappa and lambda. Kappa and gamma light chains are approximately 250 amino acids in length with an average mass of about 25 kDa. The ratio of kappa to lambda found in the immunoglobulin population varies by species.

Egyediség

Minimal cross-reaction with bovine, goat, Armenian hamster, horse, human, mouse, rat, and sheep.
The antibody reacts strongly with native primary antibodies primarily with kappa light chains. It is not suitable for detecting lambda light chains. The antibody does not react with the heavy chain of rabbit IgG. The antibody has been tested by ELISA and adsorbed to ensure minimal cross-reaction with bovine, goat, Armenian hamster, horse, human, mouse, rat, and sheep immunoglobulins.

Immunogen

Epitope: Kappa light chain
Prepared from rabbit IgG light chain.

Alkalmazás

Research Category
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies
This Mouse anti-Rabbit light chain Antibody is validated for use in ELISA, WB for the detection of Rabbit light chain.

Cél megnevezése

25 kDa

Fizikai forma

Ascites
Isolated from ascites by chromatographic procedures. Liquid in 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6.

Tárolás és stabilitás

Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt. Avoid repeated freeze/thaw cycles.

Jogi információk

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Tárolási osztály kódja

12 - Non Combustible Liquids

WGK

WGK 2

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Charles E Evans et al.
Neurobiology of aging, 75, 136-149 (2018-12-21)
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Javier Garzón-Niño et al.
International journal of molecular sciences, 24(1) (2023-01-09)
The opioid peptide β-endorphin coexists in the pituitary and brain in its αN-acetylated form, which does not bind to opioid receptors. We now report that these neuropeptides exhibited opposite effects in in vivo paradigms, in which ligands of the sigma
Jon R Ward et al.
The Journal of biological chemistry, 285(30), 23147-23158 (2010-05-25)
The processing and regulated secretion of IL-1beta are critical points of control of the biological activity of this important pro-inflammatory cytokine. IL-1beta is produced by both monocytes and macrophages, but the rate and mechanism of release differ according to the
Michael J Tuvim et al.
The Journal of biological chemistry, 284(15), 9781-9787 (2009-02-12)
Synaptotagmin 2 (Syt2) functions as a low affinity, fast exocytic Ca(2+) sensor in neurons, where it is activated by Ca(2+) influx through voltage-gated channels. Targeted insertion of lacZ into the mouse syt2 locus reveals expression in mucin-secreting goblet cells of
Jung-Lin Wu et al.
Nature communications, 7, 12526-12526 (2016-08-25)
Crosslinking of B-cell receptor (BCR) sets off an apoptosis programme, but the underlying pathways remain obscure. Here we decipher the molecular mechanisms bridging B-cell activation and apoptosis mediated by post-translational modification (PTM). We find that O-GlcNAcase inhibition enhances B-cell activation

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