MAB1254

Anti-Chymase Antibody, clone B7

clone B7, 2.4 mg/mL, Chemicon^®

• Szinonimák: Mast Cell Protease I
• UNSPSC kód: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• klón: B7, monoclonal
• application: DB; IHC
• faj reaktivitás: human
• technika/technikák: dot blot: suitable; immunohistochemistry: suitable
• citations: 2

Tulajdonságok

• biológiai forrás: mouse
• Minőségi szint: 100
• antitest forma: affinity isolated antibody
• antitest terméktípus: primary antibodies
• klón: B7, monoclonal
• faj reaktivitás: human
• gyártó/kereskedő neve: Chemicon^®
• koncentráció: 2.4 mg/mL
• technika/technikák: dot blot: suitable; immunohistochemistry: suitable
• izotípus: IgG1κ
• alkalmasság: not suitable for Western blot
• NCBI elérési szám: NM_001836.2
• UniProt elérési szám: P23946
• kiszállítva: wet ice
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... CMA1(1215)

Leírás

Általános leírás

Mast cell chymase (EC 3.4.21.39), a member of the granzyme subfamily of the S1 family of peptidases, cleaves C-terminal to Phenylalanine, Tyrosine, Tryptophan, and Leucine residues (in order of preference). Chymase is stored in Mast cell granules within the cell and is the major secreated Mast cell protease. Secreated Mast cell chymase is believed to be involved in extracellular matrix degradation, vasoactive peptide generation, and regulation of gland secreation.

Egyediség

Reacts with human mast cell chymase.

Immunogén

Chymase purified from human skin.

Alkalmazás

Anti-Chymase Antibody, clone B7 is an antibody against Chymase for use in DB, IH.

Dot blotting: 0.5-1.0 μg/mL.

Immunohistochemistry: 0.5-1.0 μg/mL. For optimal results, tissues or cytospin preparations should be fixed in Carnoy′s Fluid (60% ethanol, 30% chloroform, 10% glacial acetic acid). Not recommended for use on formaldehyde fixed tissue.

Not recommended for use on Western blots.

Optimal working dilutions must be determined by end user.

Research Category
Inflammation & Immunology

Research Sub Category
Inflammation & Autoimmune Mechanisms

Fizikai forma

Format: Purified

Purified by protein G affinity chromatography. Liquid in PBS with 20% glycerol, pH 7.4.

Tárolás és stabilitás

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt. Antibody may also be stored at -20ºC in undiluted aliquots.

Analízis megjegyzés

Control
POSITIVE CONTROL: lung, heart, skin, placenta.

Jogi információk

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable