CMA1
chymase 1, mast cell
Synonyms:
CYH, MCT1, chymase
Species:
Human CMA1 (1215), Mouse Cma1 (17228), Rat Cma1 (25627), dog CMA1 (490628), domestic guinea pig Cma1 (100135503), naked mole-rat Cma1 (101714600), domestic cat CMA1 (101084796), sheep CMA1 (100144428)
UniProtKB ID:
Gene ID:
- Human(1215) Summary: This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases. [provided by RefSeq, Jul 2008]
- Mouse(17228) chymase 1, mast cell
- Rat(25627) chymase 1, mast cell
- dog(490628) chymase 1, mast cell
- domestic guinea pig(100135503) chymase 1, mast cell
- naked mole-rat(101714600) chymase 1, mast cell
- domestic cat(101084796) chymase 1, mast cell
- sheep(100144428) chymase 1, mast cell
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CMA1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Mast Cell Chymase (CMA1) antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-Chymase Antibody, clone B7, clone B7, 2.4 mg/mL, Chemicon®,
Species Reactivity
human
Application
dot blot
immunohistochemistry
immunohistochemistry
Anti-Chymase Antibody, clone B7, biotin conjugated, clone B7, Chemicon®, from mouse,
Species Reactivity
human
Application
dot blot
immunohistochemistry
immunohistochemistry
Anti-CMA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Proteins
Product Number
Description
Species
esiRNA
Product Number
Description
Species