GF423
IL-2, Human
HumanKine®, recombinant, Xeno-free, >95% (SDS-PAGE), suitable for cell culture
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
Javasolt termékek
Általános leírás
HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
Interleukin-2 (IL-2) is commonly considered a pro-inflammatory cytokine that stimulated T-cell-dependent immune reactions and control regulatory T cells or Tregs. Structurally, IL-2 is thought to have a 4-helix-bundle-type fold and uses a novel type I cytokine receptor (IL-21R) with the common gamma chain cytokine receptor. IL-2 also may intensify Th1-mediated diseases, including autoimmune arthritis and may also be interesting clinical targets for those diseases. IL-2 has also been implicated as a possible therapy for infection and cancer. Anti-tumor therapies that include a combination of recombinant IL-2 and recombinant interferon alpha have been promising in clinical studies.
Minőség
Bioactivity assay: Determined by the dose-dependent stimulation of the proliferation of mouse CTLL-2 cells (mouse cytotoxic T cell
line). ED50 is typically 0.2-2 ng/ml.
line). ED50 is typically 0.2-2 ng/ml.
HumanKine IL-2 is manufactured using all non-animal reagents and is considered Xeno-Free
Fizikai forma
Product is presented in PBS and filtered through a 0.2 micron filter before lyophilization.
Tárolás és stabilitás
Store at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
Jogi információk
HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Analitikai tanúsítványok (COA)
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