AB2283
Anti-Tbr2 Antibody
from rabbit, purified by affinity chromatography
Szinonimák:
eomesodermin (Xenopus laevis) homolog, eomesodermin homolog (Xenopus laevis), t box, brain, 2
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(3)
About This Item
UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.41
klón:
polyclonal
application:
IHC
faj reaktivitás:
human, mouse
technika/technikák:
immunohistochemistry: suitable
citations:
36
Javasolt termékek
biológiai forrás
rabbit
Minőségi szint
antitest forma
affinity isolated antibody
antitest terméktípus
primary antibodies
klón
polyclonal
tisztítva
affinity chromatography
faj reaktivitás
human, mouse
technika/technikák
immunohistochemistry: suitable
NCBI elérési szám
UniProt elérési szám
kiszállítva
wet ice
célzott transzláció utáni módosítás
unmodified
Géninformáció
human ... EOMES(8320)
mouse ... Eomes(13813)
Általános leírás
Tbr2 (a T-domain transcription factor) is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Trb2 has been shown to play a role in the development of the neocortex and functions in the differentiation pathway of radial glia to postmitotic projection neuron.
Egyediség
This antibody recognizes Tbr2.
Immunogén
Epitope: Internal Domain
KLH-conjugated linear peptide corresponding to mouse Tbr2.
Alkalmazás
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Neuroscience
Developmental Neuroscience
This Anti-Tbr2 Antibody is validated for use in IH for the detection of Tbr2.
Minőség
Evaluated by Immunohistochemistry of human brain tissue.
Immunohistochemistry Analysis: A 1:300 dilution of Anti-Tbr2 antibody from a previous lot detected Tbr2 in mouse and human brain tissue.
Immunohistochemistry Analysis: A 1:300 dilution of Anti-Tbr2 antibody from a previous lot detected Tbr2 in mouse and human brain tissue.
Fizikai forma
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
Tárolás és stabilitás
Stable for 1 year at 2-8°C from date of receipt.
Analízis megjegyzés
Control
Human Brain Tissue
Human Brain Tissue
Egyéb megjegyzések
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Tárolási osztály kódja
12 - Non Combustible Liquids
WGK
WGK 1
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.
Dan Xu et al.
PLoS biology, 16(12), e2006613-e2006613 (2018-12-20)
Mutations of WD repeat domain 62 (WDR62) lead to autosomal recessive primary microcephaly (MCPH), and down-regulation of WDR62 expression causes the loss of neural progenitor cells (NPCs). However, how WDR62 is regulated and hence controls neurogenesis and brain size remains
Joanna Yeung et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(35), 9057-9069 (2016-09-02)
Pax6 is a prominent gene in brain development. The deletion of Pax6 results in devastated development of eye, olfactory bulb, and cortex. However, it has been reported that the Pax6-null Sey cerebellum only has minor defects involving granule cells despite
Marta Gai et al.
EMBO reports, 17(10), 1396-1409 (2016-08-27)
Correct orientation of cell division is considered an important factor for the achievement of normal brain size, as mutations in genes that affect this process are among the leading causes of microcephaly. Abnormal spindle orientation is associated with reduction of
Melanie Schoof et al.
Acta neuropathologica communications, 7(1), 199-199 (2019-12-07)
CREB (cyclic AMP response element binding protein) binding protein (CBP, CREBBP) is a ubiquitously expressed transcription coactivator with intrinsic histone acetyltransferase (KAT) activity. Germline mutations within the CBP gene are known to cause Rubinstein-Taybi syndrome (RSTS), a developmental disorder characterized
Teresa Guillamon-Vivancos et al.
Cerebral cortex (New York, N.Y. : 1991), 29(3), 1121-1138 (2018-02-08)
How the variety of neurons that organize into neocortical layers and functional areas arises is a central question in the study of cortical development. While both intrinsic and extrinsic cues are known to influence this process, whether distinct neuronal progenitor
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