AB120
Anti-Norepinephrine Antibody
serum, Chemicon®
Szinonimák:
Arterenol, Noradrenaline
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
UNSPSC kód:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Javasolt termékek
biológiai forrás
rabbit
Minőségi szint
antitest forma
serum
antitest terméktípus
primary antibodies
klón
polyclonal
faj reaktivitás
human, rat
gyártó/kereskedő neve
Chemicon®
technika/technikák
immunohistochemistry: suitable
kiszállítva
dry ice
célzott transzláció utáni módosítás
unmodified
Géninformáció
human ... SLC6A2(6530)
Általános leírás
The chemical compound norepinephrine (NC(8)O(3)H(11), also known as noradrenaline, is a catecholamine that functions as both a neurotransmitter and a hormone. It is released from the adrenal glands and also by certain neurons. It affects parts of the human brain where attention and impulsivity are controlled. This compound affects the fight-or-flight response, activating the sympathetic nervous system to directly increase heart rate, release energy from fat and increase muscle readiness.
The host of physiological changes activated by a stressful event are unleashed in part by activation of a nucleus in the brain stem called the locus ceruleus. This nucleus is the origin of most norepinephrine pathways in the brain. Neurons using norepinephrine as their neurotransmitter project bilaterally from the locus ceruleus along distinct pathways to the cerebral cortex, limbic system, and the spinal cord, among other projections.
The host of physiological changes activated by a stressful event are unleashed in part by activation of a nucleus in the brain stem called the locus ceruleus. This nucleus is the origin of most norepinephrine pathways in the brain. Neurons using norepinephrine as their neurotransmitter project bilaterally from the locus ceruleus along distinct pathways to the cerebral cortex, limbic system, and the spinal cord, among other projections.
Egyediség
Noradrenaline: reactive with noradrenaline reacted with glutaraldehyde; glutaraldehyde required in fixation for reactivity; reactivity with free noradrenaline is very poor.
The cross-reactivities were determined using either ELISA or RIA techniques, at concentration/unconjugated or conjugated amino acid concentration at half displacement.
Compound Cross-reactivity
Noradrenaline-G-BSA 1.0
Octopamine-G-BSA 0.032
Dopamine-G-BSA 0.016
Adrenaline-G-BSA 0.006
Noradrenaline 0.0002
L-Dopa-G-BSA 0.0002
p-Tryamine-G-BSA 0.0002
*The antisera was also tested for specificity using the free-floating PAP technique on rat locus coeruleus.
Abbreviations:
(BSA)= Bovine serum albumin
G)= Glutaraldehyde
The cross-reactivities were determined using either ELISA or RIA techniques, at concentration/unconjugated or conjugated amino acid concentration at half displacement.
Compound Cross-reactivity
Noradrenaline-G-BSA 1.0
Octopamine-G-BSA 0.032
Dopamine-G-BSA 0.016
Adrenaline-G-BSA 0.006
Noradrenaline 0.0002
L-Dopa-G-BSA 0.0002
p-Tryamine-G-BSA 0.0002
*The antisera was also tested for specificity using the free-floating PAP technique on rat locus coeruleus.
Abbreviations:
(BSA)= Bovine serum albumin
G)= Glutaraldehyde
Immunogen
Noradrenaline-glutaraldehyde-BSA
Alkalmazás
Anti-Norepinephrine Antibody is an antibody against Norepinephrine for use in IH.
Immunohistochemistry: 1:200-1:500 with enhanced detection. Glutaraldehyde fixation required for reactivity. Lightly fixed 4% PFA .2-5% glutaraldehyde fixed tissue works well; permeabilization with 0.1-.2% triton X-100 in block ONLY. Dilute antibody solutions in simple buffers without excess proteins or detergents.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Hormones & Receptors
Hormones & Receptors
Fizikai forma
Liquid rabbit antiserum with 0.05% sodium azide.
Tárolás és stabilitás
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Jogi információk
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Jogi nyilatkozat
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Tárolási osztály kódja
12 - Non Combustible Liquids
WGK
WGK 2
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
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