880123X

DSPE-PEG(5000) Folate

Avanti Research^™ - A Croda Brand 880123X

• Szinonimák: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-5000] (ammonium salt):methanol (9:1)
• CAS-szám: 1236288-25-7
• UNSPSC kód: 12352211
• NACRES: NA.25

Tulajdonságok

• form: liquid
• kiszerelés: pkg of 1 × 1 mL (880123X-500ug)
• gyártó/kereskedő neve: Avanti Research^™ - A Croda Brand 880123X
• koncentráció: 0.5 mg/mL (880123X-500ug)
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• SMILES string: [H][C@@](COP([O-])(OCCNC([(OCH2CH2)113]NC(CC[C@H](NC(C1=CC=C(NCC(C=N2)=NC3=C2N=C(N)NC3=O)C=C1)=O)C([O-])=O)=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+]

Leírás

Általános leírás

DSPE-PEG(5000) Folate(1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-5000]) is incorporated into liposomes as a targeting ligand for folate receptors, which acts as cellular surface markers for various cancers and myeloid leukemias. Folate targeted drug delivery is potentially used for the treatment and imaging of several cancers and inflammatory diseases. Folate conjugates are small molecules having high binding affinity for folate receptors (FR) on cell surface. Therefore, they have an ability to deliver a variety of molecular complexes to pathologic cells without affecting normal tissues.

Alkalmazás

DSPE-PEG(5000) Folate may be used:

• in preparation of folate functionalized nanoparticles (NPs)
• in synthesis of BTPEPBI-containing nanoparticles
• in preparation of paclitaxel loaded folate modified lipid-shell and polymer-core nanoparticles (FLPNPs)

Kiszerelés

5 mL Clear Glass Sealed Ampule (880123X-500ug)

Jogi információk

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Biztonsági adatok

• Piktogramok: GHS06,GHS08
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H302,H315,H319,H331,H336,H351,H361d,H370,H372
• Óvintézkedésre vonatkozó mondatok: P201 - P260 - P264 - P280 - P308 + P311 - P403 + P233
• Veszélyességi osztályok: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 1 - STOT SE 3
• Célzott szervek: Central nervous system
• Tárolási osztály kódja: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable