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380474

Sigma-Aldrich

2-Hydroxyethyl disulfide

technical grade

Szinonimák:

2,2′-Dithiodiethanol, Bis(2-hydroxyethyl) disulfide

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About This Item

Lineáris képlet:
HOCH2CH2SSCH2CH2OH
CAS-szám:
1892-29-1
Molekulatömeg:
154.25
Beilstein:
1735851
EC-szám:
217-576-6
MDL-szám:
MFCD00002906
UNSPSC kód:
12162002
PubChem Substance ID:
24863744
NACRES:
NA.23

grade

technical grade

Minőségi szint

200

Forma

liquid

törésmutató

n20/D 1.57 (lit.)

bp

158-163 °C/3.5 mmHg (lit.)

mp

25-27 °C (lit.)

sűrűség

1.261 g/mL at 25 °C (lit.)

SMILES string

OCCSSCCO

InChI

1S/C4H10O2S2/c5-1-3-7-8-4-2-6/h5-6H,1-4H2

Nemzetközi kémiai azonosító kulcs

KYNFOMQIXZUKRK-UHFFFAOYSA-N

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Általános leírás

2-Hydroxyethyldisulfide (HEDS) is an organosulfur compound ​that belongs to the class ofdialkyl disulfides and has a disulfide bond -S-S- between two hydroxyethylgroups. In material science, HEDS is used as a precursor to form self-assembledmonolayers (SAMs) on gold surfaces for applications such as corrosionprotection, lubrication, and sensors. In addition, 2-hydroxyethyl disulfide isalso used as a reducing agent in organic synthesis and as a crosslinking agentin the production of rubber compounds.

Alkalmazás

2-Hydroxyethyl disulfide can be used as:
  • A chain extender in the preparation of waterborne self-healing polyurethane, which is used in leather coating.
  • As a precursor in the synthesis of multifunctional initiator, which is used in the preparation of star polystyrenes by atom transfer radical polymerization of styrene.
  • A starting material to prepare a disulfide-based branching agent. This branching agent is used to synthesize highly branched poly(2-hydroxypropyl methacrylate).

Piktogramok

Skull and crossbonesCorrosion
GHS06,GHS05

Figyelmeztetés

Danger

Figyelmeztető mondatok

H301,H318

Veszélyességi osztályok

Acute Tox. 3 Oral - Eye Dam. 1

Tárolási osztály kódja

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Lobbanási pont (F)

233.6 °F - closed cup

Lobbanási pont (C)

112 °C - closed cup

Egyéni védőeszköz

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Válasszon a legfrissebb verziók közül:

Analitikai tanúsítványok (COA)

Lot/Batch Number
BCCK8369
BCCJ0399
BCCH5572
STBK4758
STBK2511

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2-(2-Benzothiazolylthio)ethanol 95%

Sigma-Aldrich

454451

2-(2-Benzothiazolylthio)ethanol

P C Hiestand et al.
International journal of immunopharmacology, 7(1), 141-151 (1985-01-01)
ADA 202-718, as well as HEDS and higher homologues of ADA 202-718, were found to profoundly stimulate the delayed type hypersensitivity reaction in mice when given i.p. or orally in a dose range of 0.1 - 10 mg/kg. While even
J E Brotherton et al.
Physiological chemistry and physics, 12(6), 483-495 (1980-01-01)
Incubation of horse liver aldehyde dehydrogenase (aldehyde:NAD oxidoreductase, EC 1.2.1.3) with 2-hydroxyethyl disulfide formed mixed-disulfides between protein sulfhydryl groups and beta-mercaptoethanol. Reduction of aldehyde dehydrogenase activity may be associated with formation of one, or at most two, mixed-disulfides per dehydrogenase
P C Hiestand et al.
International journal of immunopharmacology, 7(1), 129-140 (1985-01-01)
HEDS (2-hydroxyethyl disulfide) and structurally related compounds were found to affect lymphocyte proliferation and functions in vitro. HEDS, and ADA 202-718 (ethylene-2-2'-bis(dithio)bis(ethanol], were shown to stimulate the proliferation of murine spleen cells. The growth of populations of murine T-cells (thymocytes)
Cristina Lamberti et al.
Electrophoresis, 28(10), 1633-1638 (2007-05-12)
Despite the large number of papers dealing with bacterial proteomes, very few include information about proteins with alkaline pI's, because of the limits inherent in 2-DE technology. Nonetheless, analyses of in silico proteomes of many prokaryotes show a bimodal distribution
Nikola Mesecke et al.
Biochemistry, 47(5), 1452-1463 (2008-01-04)
Two novel monothiol glutaredoxins from yeast (ScGrx6 and ScGrx7) were identified and analyzed in vitro. Both proteins are highly suited to study structure-function relationships of glutaredoxin subclasses because they differ from all monothiol glutaredoxins investigated so far and share features
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