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202495

Sigma-Aldrich

Poly(ethylene glycol) methyl ether

average MN 750, methoxy, hydroxyl

Szinonimák:

Polyethylene glycol, Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG

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About This Item

Lineáris képlet:
CH3(OCH2CH2)nOH
CAS-szám:
9004-74-4
MDL-szám:
MFCD00084416
UNSPSC kód:
12162002
PubChem Substance ID:
24852093
NACRES:
NA.23

Terméknév

Poly(ethylene glycol) methyl ether, average Mn 750

gőzsűrűség

>1 (vs air)

Minőségi szint

200

gőznyomás

0.05 mmHg ( 20 °C)

Forma

paste
solid

molekulatömeg

average Mn 750

törésmutató

n20/D 1.459

viszkozitás

10.5 cSt(210 °F)(lit.)

átmeneti hőmérséklet

Tm 30 °C

sűrűség

1.094 g/mL at 25 °C

Ω-end

hydroxyl

α-end

methoxy

SMILES string

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

Nemzetközi kémiai azonosító kulcs

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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Alkalmazás

Poly(ethylene glycol) methyl ether can be used:
  • As a chain transfer agent to synthesize amphiphilic block copolymers by metal-free ring-opening oligomerization.
  • As a precursor to prepare retinoic acid-polyethylene glycol nanoassembly as an efficient drug delivery system.
  • To prepare diblock copolymer with polylactic acid, which can be applied in the field of tissue engineering and drug delivery.

Tárolási osztály kódja

10 - Combustible liquids

WGK

WGK 1

Lobbanási pont (F)

359.6 °F - closed cup

Lobbanási pont (C)

182 °C - closed cup

Egyéni védőeszköz

Eyeshields, Gloves

Válasszon a legfrissebb verziók közül:

Analitikai tanúsítványok (COA)

Lot/Batch Number
MKCW3308
0000214565
MKCV2901
MKCJ4912
MKBX5833V

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Poly(ethylene glycol) methyl ether tosylate average Mn 900

Sigma-Aldrich

729116

Poly(ethylene glycol) methyl ether tosylate

Methoxypolyethylene glycol maleimide 750

Sigma-Aldrich

712558

Methoxypolyethylene glycol maleimide

Yi Wei et al.
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The microcosmic mechanisms of protein (recombinant human growth hormone, rhGH) incomplete release and stability from amphiphilic poly(monomethoxypolyethylene glycol-co-D,L-lactide) (mPEG-PLA, PELA) microspheres were investigated. PELA with different hydrophilicities (PELA-1, PELA-2, and PELA-3) based on various ratios of mPEG to PLA were
Lei Liu et al.
International journal of pharmaceutics, 443(1-2), 175-182 (2013-01-05)
This work aims to develop curcumin (Cur) loaded biodegradable self-assembled polymeric micelles (Cur-M) to overcome poor water solubility of Cur and to meet the requirement of intravenous administration. Cur-M were prepared by solid dispersion method, which was simple and easy
Junhwa Shin et al.
Molecular pharmaceutics, 9(11), 3266-3276 (2012-10-04)
A family of 3-methoxypoly(ethylene glycol)-vinyl ether-1,2-dioleylglycerol (mPEG-VE-DOG) lipopolymer conjugates, designed on the basis of DFT calculations to possess a wide range of proton affinities, was synthesized and tested for their hydrolysis kinetics in neutral and acidic buffers. Extruded ∼100 nm
Yunki Lee et al.
Colloids and surfaces. B, Biointerfaces, 102, 585-589 (2012-10-30)
The control of biological interactions that occur at material-cell/blood interfaces is of great importance to help maximize in vitro and in vivo performance of biomedical devices. PEGylation has been extensively used as an effective surface modification tool that can alter
Pengxiang Zhao et al.
Chemical communications (Cambridge, England), 49(31), 3218-3220 (2013-03-14)
"Click" chemistry now offers access to a great variety of triazoles, and the first example of a strategy to stabilize gold nanoparticles (AuNPs) with a new 1,2,3-triazole-mPEG ligand is developed here together with preliminary examples of possible applications.
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