Ugrás a tartalomra
Merck

PARP1

poly (ADP-ribose) polymerase 1

Szinonimák:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
Faj:
UniProtKB azonosító:
Gene ID:
  • Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11545) poly (ADP-ribose) polymerase family, member 1
  • Rat(25591) poly (ADP-ribose) polymerase 1
  • Thale Cress(817690) poly [ADP-ribose] polymerase 2
  • chicken(396199) poly (ADP-ribose) polymerase 1
  • Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
  • sheep(100135697) poly (ADP-ribose) polymerase 1
  • domestic cat(101081434) poly (ADP-ribose) polymerase 1
  • Horse(100058523) poly (ADP-ribose) polymerase 1
  • dog(490385) poly (ADP-ribose) polymerase 1
  • domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
  • naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
  • cow(286764) poly (ADP-ribose) polymerase 1

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Antibodies

Cikkszám
Leírás
Faj reaktivitás
Alkalmazás
Anti-PARP1 antibody produced in rabbit, IgG fraction of antiserum,
Faj reaktivitás
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Alkalmazás
western blot
Anti-PARP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Faj reaktivitás
human
Alkalmazás
immunofluorescence
immunohistochemistry

western blot
Anti-PARP (Cleaved-Gly215) antibody produced in rabbit, affinity isolated antibody,
Faj reaktivitás
human
Alkalmazás
ELISA
western blot
Monoclonal Anti-PARP1, (N-terminal) antibody produced in mouse, clone 2C7, purified immunoglobulin, buffered aqueous solution,
Faj reaktivitás
human
Alkalmazás
ELISA
immunofluorescence

western blot
Anti- PARP1 antibody produced in rabbit, ,
Faj reaktivitás
human, mouse, rat
Alkalmazás
immunohistochemistry
western blot

Small Molecule - Inhibitor

Cikkszám
Leírás
Faj
3-Aminobenzamide, ≥99% (TLC),
Faj
mouse
6-(5H)-Phenanthridinone, technical grade,
Faj
human
Benzamide, purified by sublimation, ≥99.5%,
Faj
human
Benzamide, 99%,
Faj
human
Nicotinamide (Niacinamide), analytical standard,
Faj
human

Proteins

Cikkszám
Leírás
Faj
Monoclonal Anti-PARP1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2220, purified immunoglobulin, buffered aqueous glycerol solution,
Faj
human
Monoclonal Anti-PARP1, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2209, purified immunoglobulin, buffered aqueous glycerol solution,
Faj
human
PARP1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Faj
human
PARP-1 human, recombinant, expressed in E. coli,
Faj
human

esiRNA

Cikkszám
Leírás
Faj
MISSION® esiRNA, targeting mouse Parp1,
Faj
mouse
MISSION® esiRNA, targeting human PARP1,
Faj
human