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1380105

USP

Melatonin

United States Pharmacopeia (USP) Reference Standard

Synonyma:

N-Acetyl-5-methoxytryptamine

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About This Item

Empirický vzorec (Hillův zápis):
C13H16N2O2
Číslo CAS:
73-31-4
Molekulová hmotnost:
232.28
Beilstein/REAXYS Number:
205542
MDL number:
MFCD00005655
UNSPSC Code:
41116107
PubChem Substance ID:
329750346
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

melatonin

manufacturer/tradename

USP

mp

116.5-118 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc2[nH]cc(CCNC(C)=O)c2c1

InChI

1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)

InChI key

DRLFMBDRBRZALE-UHFFFAOYSA-N

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Související kategorie

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Melatonin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solutions for assay, performance tests, strength, and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Melatonin Tablets
  • Melatonin

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Osvědčení o analýze (COA)

Lot/Batch Number

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Sigma-Aldrich

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Melatonin
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(4), 5143-5143 (2020)
Melatonin Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(6), 5144-5144 (2013)
Ismail Gögenur et al.
Journal of pineal research, 57(1), 10-15 (2014-04-09)
The aim was to examine the effect of perioperative melatonin treatment on clinical cardiac morbidity and markers of myocardial ischemia in patients undergoing elective surgery for abdominal aortic aneurism. Reperfusion injury results in increased cardiac morbidity in patients undergoing surgery
Reuben K Wong et al.
Digestive diseases and sciences, 60(1), 186-194 (2014-08-06)
Probiotics have treatment efficacy in irritable bowel syndrome (IBS), but the exact mechanism remains obscure. One hypothesis is the mediation of melatonin levels, leading to changes in IBS symptoms. The purpose of this study was to evaluate the effects of
Chun-Ta Huang et al.
Sleep, 37(9), 1513-1523 (2014-08-22)
Sleep deprivation is common in patients with neuropathic pain, but the effect of sleep deprivation on pathological pain remains uncertain. This study investigated whether sleep deprivation aggravates neuropathic symptoms and enhances microglial activation in the cuneate nucleus (CN) in a
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