14927

Serotonin

analytical standard

• Synonyma: 3-(2-Aminoethyl)-5-hydroxyindole, 5-HT, 5-Hydroxytryptamine
• Empirický vzorec (Hillův zápis): C₁₀H₁₂N₂O
• Číslo CAS: 50-67-9
• Molekulová hmotnost: 176.22
• UNSPSC Code: 85151701
• NACRES: NA.24
• PubChem Substance ID: 329750658
• EC Number: 200-058-9
• Beilstein/REAXYS Number: 143524
• MDL number: MFCD00055054

Vlastnosti

• grade: analytical standard
• Quality Segment: 100
• description: Drug Control: Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet
• assay: ≥95.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• drug control: Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• impurities: ≤1.0% water (calc. from elemental analysis)
• format: neat
• storage temp.: 2-8°C
• SMILES string: OC1=CC=C(NC=C2CCN)C2=C1
• InChI: 1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
• InChI key: QZAYGJVTTNCVMB-UHFFFAOYSA-N

Popis

General description

Serotonin, also known as 5-hydroxytryptamine, is an important biogenic monoamine neurotransmitter and a neuromodulator, found in the central nervous system. It is involved in regulating various physiological processes such as appetite, anxiety, sleep, mood, and blood pressure. A decrease in serotonin levels might result in disorders such as obesity, schizophrenia, and depression.

Application

This analytical standard can also be used as follows:

• Electrochemical detection of serotonin in urine samples using a glassy carbon electrode (GCE) coated with multiwalled-carbon-nanotubes (MWCNT) doped with nickel, zinc, and iron oxide nanoparticles by a cyclic voltammetry procedure
• Development and validation of an ultra high-performance liquid chromatography-tandem mass spectrometry method to determine serotonin in raw and roasted samples of a variety of nuts, along with commercial nut products
• Designing of RuO₂ nanowires/CeO₂-AuNFs nanofibers/graphene oxide/functionalized multiwalled carbon nanotubes modified screen-printed carbon electrode for the multi-residue analysis of serotonin, dopamine, and ascorbic acid in cerebrospinal fluid and vitamin C tablet samples
• Construction of a low-cost glassy carbon electrode (GCE) modified with a nanoparticulate film of nanodiamonds and gold nanoparticles anchored to GCE using casein for the quantification of serotonin in urine samples
• Determination of serotonin in urine samples using a two-dimensional capillary isotachophoresis-capillary zone electrophoresis procedure coupled with tandem mass spectrometry (MS/MS)

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Bezpečnostní informace

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301,H361
• pcodes: P202 - P264 - P270 - P280 - P301 + P310 - P405
• Hazard Classifications: Acute Tox. 3 Oral - Repr. 2
• Skladovací třída: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable