PHR2241

Melatonin Related Compound A

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyma: 5-Methoxytryptamine, 2-(5-Methoxyindol-3-yl)ethylamine, 3-(2-Aminoethyl)-5-methoxyindole, 5-MOT, 5-Methoxyindole-3-ethanamine, Deacetylmelatonin, NSC 56422
• Empirický vzorec (Hillův zápis): C₁₁H₁₄N₂O
• Číslo CAS: 608-07-1
• Molekulová hmotnost: 190.24
• Beilstein/REAXYS Number: 145587
• MDL number: MFCD00005662
• UNSPSC Code: 41116107
• NACRES: NA.24

Vlastnosti

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to USP 1380116
• API family: melatonin
• form: solid
• CofA: current certificate can be downloaded
• packaging: pkg of 50 mg
• mp: 121-123 °C (lit.)
• application(s): pharmaceutical small molecule
• storage temp.: -10 to -25°C
• SMILES string: COc1ccc2[nH]cc(CCN)c2c1
• InChI: 1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3
• InChI key: JTEJPPKMYBDEMY-UHFFFAOYSA-N

Popis

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

Reactant for preparation of:

• Carboline disaccharide domain of shishijimicin A
• Melatonin analogs for the reduction of intraocular pressure
• 5-HT4 receptor ligands
• inhibitors of sortase A and isocitrate lyase
• Therapeutic agents for treatment of ischemia/reperfusion (I/R) injury
• Aurora and epidermal growth factor receptor kinase inhibitors
• Agents for the treatment of human papillomavirus infection
• Manzamine analogues for the control of neuroinflammation and cerebral infections
• Inhibitors of pro-inflammatory cytokines
• Tacrine-melatonin hybrids as multifunctional agents for alzheimer′s disease

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3413 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

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Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable