8.22291

1-Naphthylamine

for synthesis

• Synonyma: 1-Naphthylamine, 1-Aminonaphthalene
• Empirický vzorec (Hillův zápis): C₁₀H₉N
• Číslo CAS: 134-32-7
• Molekulová hmotnost: 143.19
• MDL number: MFCD00004016
• UNSPSC Code: 12352116
• EC Index Number: 205-138-7
• NACRES: NA.22

Vlastnosti

• vapor pressure: 0.003 hPa ( 20 °C)
• Quality Level: 200
• assay: ≥99.0% (GC)
• form: solid
• autoignition temp.: 460 °C
• potency: 680 mg/kg LD₅₀, oral (Rat)
• pH: 7.1 (20 °C, 1 g/L in H₂O)
• bp: 301 °C/1013 hPa
• mp: 48-50 °C
• transition temp: flash point 157 °C
• solubility: 1.7 g/L
• density: 1.15 g/cm³ at 20 °C
• bulk density: 560 kg/m³
• storage temp.: 2-30°C
• SMILES string: Nc1c2c(ccc1)cccc2
• InChI: 1S/C10H9N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,11H2
• InChI key: RUFPHBVGCFYCNW-UHFFFAOYSA-N

Popis

Application

• Cobalt (II)–catalyzed C8H alkoxylation of 1-naphthylamine derivatives with alcohols: An efficient methodology for the cobalt-catalyzed C-H bond alkoxylation of 1-naphthylamine derivatives using readily available alcohols, allowing for the synthesis of 8-alkoxy-1-naphthylamine derivatives (T Zhang, H Zhu, F Yang, Y Wu, Y Wu - Tetrahedron, 2019 - Elsevier) Read more.
• Palladium-catalyzed regioselective C8–H amination of 1-naphthylamine derivatives with aliphatic amines: This study presents a palladium-catalyzed method for regioselective amination of 1-naphthylamine derivatives, yielding products in good yield and demonstrating the versatility in C-H functionalization chemistry (Z Li, S Sun, H Qiao, F Yang, Y Zhu, J Kang, Y Wu… - Organic Letters, 2016 - ACS Publications) Read more.
• Experimental and simulation study on the solubility of 1-naphthylamine in twelve neat solvents: This research provides a comprehensive experimental and simulation study on the solubility of 1-naphthylamine, contributing to better understanding of its thermodynamic properties in various solvents (B Mei, Y Wang, J Zhou, X Yang, Y Yu, L Xu… - Journal of Molecular Liquids, 2024 - Elsevier) Read more.

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Melting range (lower value): ≥ 48 °C
Melting range (upper value): ≤ 50 °C
2-Naphthylamine (GC, area%): ≤ 0.10 % (a/a)
Identity (IR): passes test
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

Bezpečnostní informace

• pictograms: GHS07,GHS08,GHS09
• signalword: Danger
• hcodes: H302 - H350 - H411
• pcodes: P202 - P264 - P273 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1A
• Storage Class: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: 314.6 °F - closed cup
• flash_point_c: 157 °C - closed cup