O6503

L-Ornithine monohydrochloride

BioReagent, suitable for cell culture, ≥99%

• Sinónimos: (S)-2,5-Diaminopentanoic acid monohydrochloride
• Fórmula empírica (notación de Hill): C₅H₁₂N₂O₂ · HCl
• Número de CAS: 3184-13-2
• Peso molecular: 168.62
• Beilstein: 3625847
• Número CE: 221-678-6
• Número MDL: MFCD00064562
• Código UNSPSC: 12352209
• ID de la sustancia en PubChem: 24898036
• NACRES: NA.75

Propiedades

• origen biológico: microbial
• Nivel de calidad: 300
• Línea del producto: BioReagent
• Ensayo: ≥99%
• Formulario: powder
• envase: pkg of 100 g; pkg of 25 g
• técnicas: cell culture | mammalian: suitable
• impurezas: ammonia and citrulline, essentially free
• solubilidad: H₂O: soluble 50 mg/mL, clear, colorless to very faintly yellow
• cadena SMILES: Cl.NCCC[C@H](N)C(O)=O
• InChI: 1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1
• Clave InChI: GGTYBZJRPHEQDG-WCCKRBBISA-N

Descripción

Descripción general

L-Ornithine is the functional metabolite of L-arginine.[1]

L-Ornithine is an amino acid that is not coded for by the genetic code. It is formed during the decomposition of argininine by arginase and participates in the urea cycle. Ornithine is the starting point for the formation of a family of polyamines that include spermine, spermidine and putrescine.

Aplicación

L-Ornithine monohydrochloride has been used:

• as a supplement in Dulbecco′s modified eagle medium (DMEM) for cell growth assays[2]
• as a component in the standard medium for primary human hepatocytes (PHH) culture[3]
• as a creatine synthesis inhibitor[4]

Acciones bioquímicas o fisiológicas

L-ornithine acts as a precursor for polyamines.[5] It may modulate the intake of food as an acute satiety signal in the neonatal chick brain.[1]

L-Ornithine is used as a media supplement to support the biosynthesis of polyamines.

Otras notas

Product of arginine degradation by arginase

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)