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A8625

Sigma-Aldrich

N-Acetil-D-glucosamina

≥99% (HPLC)

Sinónimos:

2-Acetamido-2-desoxi-D-glucosa, D-GlcNAc

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10 MG
$32.100
5 G
$150.000
25 G
$505.000

$32.100

Fecha estimada de envío31 de marzo de 2025

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10 MG
$32.100
5 G
$150.000
25 G
$505.000

About This Item

Fórmula empírica (notación de Hill):
C8H15NO6
Número de CAS:
7512-17-6
Peso molecular:
221.21
Beilstein/REAXYS Number:
1727589
EC Number:
231-368-2
MDL number:
MFCD00061615
UNSPSC Code:
12352201
PubChem Substance ID:
24891348
NACRES:
NA.25

$32.100

Fecha estimada de envío31 de marzo de 2025

Solicitar un pedido a granel

biological source

crab (red)

Quality Level

200

assay

≥99% (HPLC)

form

powder

technique(s)

HPLC: suitable

color

white to off-white

mp

211 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear to very slightly hazy (colorless to faint yellow solution)

storage temp.

−20°C

SMILES string

CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

InChI

1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8?/m1/s1

InChI key

OVRNDRQMDRJTHS-RTRLPJTCSA-N

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General description

La N-acetilglucosamina (GlcNAc) es el derivado acetilado de la glucosamina (GlcN). Es un componente importante de los proteoglucanos, las glucoproteínas, los glucosaminoglucanos (GAG) y otras unidades estructurales que se encuentran en el tejido conjuntivo.

application

La N-acetil-D-glucosamina se ha utilizado:
  • como azúcar para la inhibición competitiva en histoquímica con lectinas
  • como componente en el medio Barbour-Stonner-Kelly (BSK) para cultivar cepas de las espiroquetas Borrelia burgdorferi
  • como componente del tampón de unión para suspender cepas de Streptococcus pneumoniae destinado al ensayo de inhibición para examinar la especificidad de unión de la ficolina M a cepas de S. pneumoniae

Biochem/physiol Actions

La N-acetilglucosamina (GlcNAc) se utiliza principalmente en las industrias alimentaria, cosmética y farmacéutica.

Other Notes

Si desea conocer por completo nuestra amplia gama de monosacáridos para su investigación, le recomendamos que visite nuestra página de categoría Carbohidratos .

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000401912
0000401912
0000410037
0000410037
0000398305

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Visite la Librería de documentos

Kwang-Hyup Lee et al.
Tissue & cell, 48(4), 361-369 (2016-05-29)
The morphological characteristics and glycoconjugate composition of the vomeronasal organ (VNO) of the horse was investigated using histological, immunohistochemical, and lectin histochemical methods. The VNO is bilaterally located at the base of the nasal septum, has a tubular structure surrounded
Colette Cywes-Bentley et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(24), E2209-E2218 (2013-05-30)
Microbial capsular antigens are effective vaccines but are chemically and immunologically diverse, resulting in a major barrier to their use against multiple pathogens. A β-(1→6)-linked poly-N-acetyl-d-glucosamine (PNAG) surface capsule is synthesized by four proteins encoded in genetic loci designated intercellular
Lucy G Weaver et al.
Carbohydrate research, 371, 68-76 (2013-03-26)
Poly-N-acetylglucosamine (PNAG) saccharides are an important constituent of bacterial biofilms, such as those produced by Staphylococcus aureus. We have developed a simple two-step iterative method for the synthesis of β-(1→6)-glucosamine oligosaccharides that are structurally similar to PNAG. We illustrate the
Bingwu Yu et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 228, 159-165 (2013-01-09)
Strong (1)H-(1)H coupling can significantly reduce the accuracy of (1)J(CH) measured from frequency differences in coupled HSQC spectra. Although accurate (1)J(CH) values can be extracted from spectral simulation, it would be more convenient if the same accurate (1)J(CH) values can
Yasuhito Onodera et al.
The Journal of clinical investigation, 124(1), 367-384 (2013-12-10)
There is a considerable resurgence of interest in the role of aerobic glycolysis in cancer; however, increased glycolysis is frequently viewed as a consequence of oncogenic events that drive malignant cell growth and survival. Here we provide evidence that increased
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Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. What is the physicochemical method or principle used to determine optical rotation in this product, could you confirm that the product is released with polarimetry?

    1 answer

    1. The method of analysis for this product is considered proprietary, however details and conditions are published in the Certificate of Analysis. See the link below for a sample CofA.
      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/A8625-5G0000185218.pdf

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