T1505

Tetraisopropylpyrophosphoramid

butyrylcholinesterase inhibitor

• Synonym(e): Tetra(monoisopropyl)pyrophosphortetramide, iso-OMPA
• Empirische Formel (Hill-System): C₁₂H₃₂N₄O₃P₂
• CAS-Nummer: 513-00-8
• Molekulargewicht: 342.36
• EG-Nummer: 208-149-5
• MDL-Nummer: MFCD00048272
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 24278724
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic
• mp (Schmelzpunkt): 149-151 °C
• Lagertemp.: −20°C
• SMILES String: CC(C)NP(=O)(NC(C)C)OP(=O)(NC(C)C)NC(C)C
• InChI: 1S/C12H32N4O3P2/c1-9(2)13-20(17,14-10(3)4)19-21(18,15-11(5)6)16-12(7)8/h9-12H,1-8H3,(H2,13,14,17)(H2,15,16,18)
• InChIKey: IOIMDJXKIMCMIG-UHFFFAOYSA-N
• Angaben zum Gen: human ... ACHE(43) , BCHE(590)

Beschreibung

Anwendung

Tetraisopropyl pyrophosphoramide has been used:

• as a butyrylcholinesterase inhibitor to determine the proportions of butyrylcholinesterase (BChE) in cat and tiger plasma[1]
• to inhibit wild-type BChE in acetylcholinesterase assay[2]
• to selectively block the enzymatic activity of AChE[3]

Biochem./physiol. Wirkung

Selective inhibitor of butyrylcholinesterase

Warnhinweis

WARNING: Extremely hazardous! Be aware of the risk and familiar with safety procedures before you use this product.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H300 + H310 + H330
• P-Sätze: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Gefahreneinstufungen: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
• Lagerklassenschlüssel: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges