1021204

4-Aminophenol

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): 4-Hydroxyaniline
• Fórmula linear: H₂NC₆H₄OH
• Número CAS: 123-30-8
• Peso molecular: 109.13
• Beilstein: 385836
• Número MDL: MFCD00007869
• Código UNSPSC: 41116107
• ID de substância PubChem: 329748983
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: paracetamol, acetaminophen, mesalazine
• fabricante/nome comercial: USP
• pf: 185-189 °C (lit.)
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• cadeia de caracteres SMILES: Nc1ccc(O)cc1
• InChI: 1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
• chave InChI: PLIKAWJENQZMHA-UHFFFAOYSA-N

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.4-Aminophenol is the principal degradation product of acetaminophen, formed as an impurity during its hydrolysis.

Aplicação

This USP reference standard is intended for use in specified quality tests and assays.
Also used to prepare standard and system suitability solutions to test for the presence of 4-aminophenol as an impurity in various pharmaceutical dosage forms of acetaminophen, according to the United States Pharmacopeia (USP) monographs:

• Mesalamine
• Acetaminophen Tablets
• Acetaminophen Oral Suspension
• Tramadol Hydrochloride and Acetaminophen Tablets

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS08,GHS07,GHS09
• Palavra indicadora: Warning
• Frases de perigo: H302 + H332,H317,H341,H373,H410
• Declarações de precaução: P273 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P308 + P313
• Classificações de perigo: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Skin Sens. 1 - STOT RE 2
• Órgãos-alvo: Kidney
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable