PHR1530

Acetaminophen Related Compound D

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinônimo(s): Acetanilide, N-Phenylacetamide
• Fórmula linear: CH₃CONHC₆H₅
• Número CAS: 103-84-4
• Peso molecular: 135.16
• Beilstein: 606468
• Número CE: 203-150-7
• Número MDL: MFCD00008674
• Código UNSPSC: 41116107
• ID de substância PubChem: 329823442
• NACRES: NA.24

Propriedades

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to USP 1003042
• densidade de vapor: 4.65 (vs air)
• pressão de vapor: 1 mmHg ( 114 °C)
• descrição: API family: acetaminophen
• família API: acetaminophen, paracetamol
• Certificado de análise (CofA): current certificate can be downloaded
• temperatura de autoignição: 1004 °F
• embalagem: pkg of 200 mg
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• p.e.: 304 °C (lit.)
• pf: 113-115 °C (lit.)
• aplicação(ões): pharmaceutical (small molecule)
• Formato: neat
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: CC(=O)Nc1ccccc1
• InChI: 1S/C8H9NO/c1-7(10)9-8-5-3-2-4-6-8/h2-6H,1H3,(H,9,10)
• chave InChI: FZERHIULMFGESH-UHFFFAOYSA-N

Descrição

Descrição geral

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

It is an impurity of the widely used antipyretic and analgesic drug acetaminophen, also known as paracetamol.[1]

Aplicação

This pharmaceutical secondary standard can also be used as follows:

• Detection and quantification of paracetamol, phenylephrine hydrochloride, and paracetamol impurities in pharmaceutical formulations using four chemometric-based spectrophotometric methods
• Simultaneous determination of paracetamol and phenylephrine hydrochloride in the presence of paracetamol-related impurities using capillary zone electrophoresis (CZE) in their combined tablet forms[2]

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAA3648 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302
• Declarações de precaução: P301 + P312 + P330
• Classificações de perigo: Acute Tox. 4 Oral
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 321.8 °F - closed cup
• Ponto de fulgor (°C): 161 °C - closed cup