Unfortunately, the solution stability of this product at -20°C is not determined internally. However, various sources suggest frozen aliquots stored at -20°C are stable for at least 3-4 months. It is strongly recommend to protect the solution from light.
H0135
Hidrocortisona
γ-irradiated, powder, BioXtra, suitable for cell culture
Sinônimo(s):
11β,17α,21-Tri-hidroxipregna-4-eno-3,20-diona, 17-Hidroxicorticosterona, 4-Pregneno-11β,17α,21-triol-3,20-diona, Composto F de Kendall, Cortisol, Substância M de Reichstein
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1 MG
R$ 464,00
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1 MG
R$ 464,00
About This Item
Fórmula empírica (Notação de Hill):
C21H30O5
Número CAS:
Peso molecular:
362.46
Beilstein:
1354819
Número CE:
Número MDL:
Código UNSPSC:
12352209
ID de substância PubChem:
NACRES:
NA.77
fonte biológica:
synthetic (organic)
Formulário:
powder
Ensaio:
≥80% (HPLC)
Produtos recomendados
fonte biológica
synthetic (organic)
Nível de qualidade
esterilidade
γ-irradiated
linha de produto
BioXtra
Ensaio
≥80% (HPLC)
Formulário
powder
técnica(s)
cell culture | mammalian: suitable
pf
211-214 °C (lit.)
solubilidade
ethanol: 1 mg/mL, clear
Condições de expedição
ambient
temperatura de armazenamento
room temp
cadeia de caracteres SMILES
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO
InChI
1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
chave InChI
JYGXADMDTFJGBT-VWUMJDOOSA-N
Informações sobre genes
human ... ABCB1(5243) , CYP3A4(1576) , NR3C1(2908) , SERPINA6(866)
mouse ... Abcb1a(18671) , Abcb1b(18669) , Ifng(15978) , Nos2(18126)
rat ... Ar(24208) , Nr3c1(24413)
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Descrição geral
Hydrocortisone for use in epithelial and endothelial adherent cell culture applications.
Aplicação
Hydrocortisone is used for the following applications:
- Used in myogenic induction and identification[1]
- Used in long-term stromal cultures and methylcellulose cultures (one of the components in the culture medium)[2]
- Used in adipogenic differentiation (one of the components in adipogenic medium)[3]
- Used in cell culture: The human mammary epithelial cell MCF-10A cells were maintained in DMEM/F12 and supplemented with hydrocortisone along with other components[4]
- The SUM149 cell line was established from a primary IBC and grown in FBS supplemented with Ham′s F12 medium containing insulin and hydrocortisone[5]
- Used in differentiation assays of melanoma spheroid cells[6]
Ações bioquímicas/fisiológicas
Glicocorticoide primário secretado pelo córtex adrenal. Tem três vezes a potência anti-inflamatória da corticosterona, mas uma potência de retenção de Na2+ muito menor.
forma física
powder-RT; stock-frozen in working aliquots, avoid repeated freeze/thaw
Reconstituição
To prepare 50 μg/mL stock solution; add 1 mL absolute ethanol, gently swirl to dissolve, add 19 mL sterile medium while mixing.
produto relacionado
Nº do produto
Descrição
Preços
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Repr. 1A - STOT RE 2
Órgãos-alvo
Adrenal gland,Bone marrow
Código de classe de armazenamento
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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How long is the 50 μg/mL stock solution (1 mL absolute ethanol + 19 mL sterile medium) stable when stored in frozen aliquots at -20°C?
1 answer-
Helpful?
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What are the recommended storage conditions for stock solutions of item H0135, Hydrocortisone?
1 answer-
The stock solutions can be stored at 4°C and are stable for up to 1 month.
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