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E9502

Sigma-Aldrich

EPPS

≥99.5% (titration)

Sinônimo(s):

4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid, 4-(2-Hydroxyethyl)piperazine-1-propanesulfonic acid, N-(2-Hydroxyethyl)piperazine-N′-(3-propanesulfonic acid), HEPPS

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About This Item

Fórmula empírica (Notação de Hill):
C9H20N2O4S
Número CAS:
16052-06-5
Peso molecular:
252.33
Beilstein:
3957385
Número CE:
240-198-8
Número MDL:
MFCD00006160
Código UNSPSC:
12161700
ID de substância PubChem:
24894698
NACRES:
NA.25

Nível de qualidade

400

Ensaio

≥99.5% (titration)

Formulário

powder

pH

7.3-8.7

faixa de pH útil

7.3-8.7

pKa (25 °C)

8.0

pKa 

8

pf

237-239 °C (lit.)

solubilidade

H2O: 25 g + 50 mL, clear, colorless

λmax

A290 at ≤0.1 (C=33% w/w)

aplicação(ões)

diagnostic assay manufacturing

cadeia de caracteres SMILES

OCCN1CCN(CCCS(O)(=O)=O)CC1

InChI

1S/C9H20N2O4S/c12-8-7-11-5-3-10(4-6-11)2-1-9-16(13,14)15/h12H,1-9H2,(H,13,14,15)

chave InChI

OWXMKDGYPWMGEB-UHFFFAOYSA-N

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Categorias relacionadas

Aplicação

EPPS has been used:
  • to verify the effect of pH variation on the proteolytic activity of the posterior midgut (PMG) contents and anterior midgut (AMG) tissue homogenate
  • to prepare a destaining buffer to destain intensely stained gel pieces
  • to prepare digestion buffer for in-gel enzymatic digestion
  • to reconstitute the digested peptides for the processing of brain-derived extracellular vesicle (EV) proteins and 16-plex isobaric tandem mass tag (TMT) peptide labeling

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
0000409395
0000409395
0000401814
0000401816
0000401818

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CHES ≥99.0% (titration)

Sigma-Aldrich

C2885

CHES

HEPES ≥99.5% (titration)

Sigma-Aldrich

H3375

HEPES

Bernhard Sissolak et al.
Journal of industrial microbiology & biotechnology, 46(8), 1167-1178 (2019-06-09)
Recombinant monoclonal antibodies are predominantly produced in mammalian cell culture bioprocesses. Post-translational modifications affect the micro-heterogeneity of the product and thereby influence important quality attributes, such as stability, solubility, pharmacodynamics and pharmacokinetics. The analysis of the surface charge distribution of
Amir Ata Saei et al.
Nature communications, 10(1), 5715-5715 (2019-12-18)
Deconvolution of targets and action mechanisms of anticancer compounds is fundamental in drug development. Here, we report on ProTargetMiner as a publicly available expandable proteome signature library of anticancer molecules in cancer cell lines. Based on 287 A549 adenocarcinoma proteomes
YoungSoo Kim et al.
Science advances, 5(4), eaav1388-eaav1388 (2019-04-20)
Detection of amyloid-β (Aβ) aggregates contributes to the diagnosis of Alzheimer disease (AD). Plasma Aβ is deemed a less invasive and more accessible hallmark of AD, as Aβ can penetrate blood-brain barriers. However, correlations between biofluidic Aβ concentrations and AD
Heeseon An et al.
Molecular cell, 74(5), 891-908 (2019-04-23)
Cells respond to nutrient stress by trafficking cytosolic contents to lysosomes for degradation via macroautophagy. The endoplasmic reticulum (ER) serves as an initiation site for autophagosomes and is also remodeled in response to nutrient stress through ER-phagy, a form of
Alban Ordureau et al.
Molecular cell, 77(5), 1124-1142 (2020-03-07)
The ubiquitin ligase Parkin, protein kinase PINK1, USP30 deubiquitylase, and p97 segregase function together to regulate turnover of damaged mitochondria via mitophagy, but our mechanistic understanding in neurons is limited. Here, we combine induced neurons (iNeurons) derived from embryonic stem
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