C9017
Concanavalin A from Canavalia ensiformis (Jack bean)
Sepharose™ conjugate, buffered aqueous suspension
Sinônimo(s):
ConA
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About This Item
Código UNSPSC:
12161501
NACRES:
NA.32
Produtos recomendados
fonte biológica
Canavalia ensiformis
conjugado
Sepharose™ conjugate
forma
buffered aqueous suspension
contém
20% ethanol as preservative
Extensão da rotulagem
10-16 mg per mL
matriz
Sepharose 4B
ativação da matriz
cyanogen bromide
ligação da matriz
amino
espaçador de matriz
1 atom
capacidade
≥25 mg/mL binding capacity (thyroglobulin)
temperatura de armazenamento
2-8°C
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Aplicação
Used for the purification of glycoproteins containing mannose.
Ações bioquímicas/fisiológicas
Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.
forma física
Suspension in 0.1 M acetate buffer, pH 6.0, containing 1 M NaCl, and 1 mM each of CaCl2 , MgCl2, and MnCl2
Nota de análise
Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca2+ and Mn2+ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C.
Informações legais
Sepharose is a trademark of Cytiva
produto relacionado
Nº do produto
Descrição
Preços
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
Código de classe de armazenamento
3 - Flammable liquids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
102.2 °F
Ponto de fulgor (°C)
39 °C
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