L1882

Lectin from Triticum vulgaris (wheat)

agarose conjugate, saline suspension

• Sinônimo(s): WGA, Wheat germ agglutinin
• Código UNSPSC: 12352202
• NACRES: NA.32

Propriedades

• conjugado: agarose conjugate
• Nível de qualidade: 200
• Formulário: saline suspension
• Extensão da rotulagem: 5-10 mg per mL
• Matriz: cross-linked 4% beaded agarose
• ativação da matriz: cyanogen bromide
• capacidade: ≥0.1 mg/mL binding capacity (ovomucoid)
• temperatura de armazenamento: 2-8°C

Descrição

Descrição geral

Lectins are carbohydrate-binding proteins, found in fungi, plants and animals. The secondary structure of a lectin is rich in β-strands and possesses a carbohydrate binding sites on the surface.[1]

Aplicação

Used for the purification of glycoproteins containing (D-N-acetylglucosamine)₂ or N-acetylneuraminic acid.

Ações bioquímicas/fisiológicas

Lectins are known to be useful in glycoconjugate characterizing, imaging and targeting. They specifically interact with oligosaccharides, glycoproteins and glycolipids. Hence, lectins are used in microarray assays, enabling efficient glycome profiling. In plants and fungi, lectins defend against pathogens or feeders. They are also involved in host recognition and tissue adhesion.[1]

WGA is not blood group specific but has an affinity for N-acetyl-β-D-glucosaminyl residues and N-acetyl-β-D-glucosamine oligomers. WGA contains no protein-bound carbohydrate.

forma física

Suspension in 1.0 M NaCl containing 15 mM sodium azide

Nota de preparo

Conjugates are prepared from affinity purified lectin.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Equipamento de proteção individual: Eyeshields, Gloves