C7505

L-Cystathionine

≥98% (TLC), suitable for UHPLC

• Sinônimo(s): (R)-S-(2-Amino-2-carboxyethyl)-L-homocysteine
• Fórmula empírica (Notação de Hill): C₇H₁₄N₂O₄S
• Número CAS: 56-88-2
• Peso molecular: 222.26
• Beilstein: 2505200
• Número CE: 200-295-8
• Número MDL: MFCD00036685
• Código UNSPSC: 12352209
• ID de substância PubChem: 24892965
• NACRES: NA.26

Propriedades

• product name: L-Cystathionine, ≥98% (TLC)
• Ensaio: ≥98% (TLC)
• forma: powder
• técnica(s): UHPLC: suitable
• cor: white
• pf: >300 °C
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: N[C@@H](CCSC[C@H](N)C(O)=O)C(O)=O
• InChI: 1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5-/m0/s1
• chave InChI: ILRYLPWNYFXEMH-WHFBIAKZSA-N

Descrição

Aplicação

L-Cystathionine has been used in ultra-performance liquid chromatography for the validation of cystathionine and the correlation of its abundance with vertebrate metamorphosis. It has also been used as an inhibitor of sinusoidal GSH (glutathione) carrier to signify that thiol redox state imbalance is associated with the modulation of autophagy in carcinoma cells.

Ações bioquímicas/fisiológicas

L-Cystathionine is an intermediate in the biosynthesis of L-cysteine and methionine. It is used as a substrate to differentiate and analyze cystathionine γ-lyase(s). L-Cystathionine is an important non-protein amino acid and is associated with metabolic disorders. In recent studies, L-cystathionine is believed to be the precursor of cyclic imino acid cyclothionine. Cystathioninuria is characterized with imino acid cyclothionine excretion in the urine.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)