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A9080

Sigma-Aldrich

Albumin solution human

30% in 0.85% sodium chloride, protease free

Sinônimo(s):

HSA

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About This Item

Número CAS:
Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.25

fonte biológica

human

Nível de qualidade

forma

liquid

concentração

29.5-35.0% protein (biuret)
30% in 0.85% sodium chloride

técnica(s)

ELISA: suitable
tissue culture: suitable
western blot: suitable

Impurezas

HIV I and HIVII, HCV and HBsAg, tested negative

nº de adesão UniProt

temperatura de armazenamento

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

chave InChI

QYSGYZVSCZSLHT-UHFFFAOYSA-N

Informações sobre genes

human ... ALB(213)

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Descrição geral

Albumin is the most copious protein in blood plasma. Liver produces human albumin. Human serum albumin undergoes three different post-translational modifications: oxidation, glycation, and S-nitrosylation. Modifications usually occur on the surface of the globular protein, and do not significantly affect conformation. However, modification strongly affects binding of fatty acids and drug molecules.
Human serum albumin undergoes three different post-translational modifications: oxidation, glycation, and S-nitrosylation. Modifications usually occur on the surface of the globular protein, and do not significantly affect conformation. However, modification strongly affects binding of fatty acids and drug molecules.

Outras notas

View more information on human serum albumin.

Exoneração de responsabilidade

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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T. Scott and M. Eagleson
Concise encyclopedia of biochemistry, 19-20 (1988)
A A Spector et al.
Journal of lipid research, 10(1), 56-67 (1969-01-01)
We have studied the binding of long-chain free fatty acids (FFA) to crystalline bovine serum albumin (BSA) that had been extracted with charcoal to remove endogenous fatty acids. The data were analyzed in terms of a model consisting of six
Copper-binding properties of bovine serum albumin and its amino-terminal peptide fragment.
T Peters et al.
The Journal of biological chemistry, 242(7), 1574-1578 (1967-04-10)
Víctor Collado-Díaz et al.
Frontiers in pharmacology, 12, 613449-613449 (2021-04-20)
The cardiovascular toxicity of Abacavir is related to its purinergic structure. Purinergic P2X7-receptors (P2X7R), characterized by activation by high concentrations of ATP and with high plasticity, seem implicated. We appraise the nature of the interplay between Abacavir and P2X7R in
Harald Olsen et al.
BMC clinical pharmacology, 4, 4-4 (2004-03-30)
Albumin is the most abundant protein in blood plasma, and due to its ligand binding properties, serves as a circulating depot for endogenous and exogenous (e.g. drugs) compounds. Hence, the unbound drug is the pharmacologically active drug. Commercial human albumin

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