GHRA-88HK

Human Ghrelin (ACTIVE) RIA

• Código UNSPSC: 12161503
• eCl@ss: 32161000
• NACRES: NA.84

Propriedades

• grau: for protein analysis
• Nível de qualidade: 100
• descrição: ED₈₀ = 27 ± 7pg/mL ED₅₀=125 ± 33 pg/mL ED₂₀=652 ± 179 pg/mL ; analytes available: Ghrelin; 10-2000 pg/mL (standard curve range)
• Características: accuracy 83–114%
• reatividade de espécies: human
• faixa de medição de sensibilidade: 10 pg/mL
• técnica(s): radioimmunoassay: suitable
• nº de adesão UniProt: Q9UBU3
• método de detecção: radioactive

Descrição

Descrição geral

FUNCTION: SwissProt: Q9UBU3 # Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity).
SIZE: 117 amino acids; 12911 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy.
PTM: O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28- C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28- C10:1, may be modified with a singly unsaturated carboxylic acid. & Amidation of Leu-98 is essential for obestatin activity (By similarity).
SIMILARITY: SwissProt: Q9UBU3 ## Belongs to the motilin family.

Aplicação

Two-day disequilibrium assay at 4°C. Sample volume: ≤ 100 μL Plasma (collected on ice) recommended

Nota de análise

Linearity 100–142.5%

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Pictogramas: GHS02,GHS06,GHS08,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H226,H302 + H332,H311,H370,H373,H411
• Declarações de precaução: P210 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P308 + P311
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Flam. Liq. 3 - STOT RE 2 Inhalation - STOT SE 1
• Órgãos-alvo: Eyes,Central nervous system, Respiratory Tract
• Código de classe de armazenamento: 3 - Flammable liquids