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437695

Sigma-Aldrich

Anti-Lipoic Acid Rabbit pAb

liquid, Calbiochem®

Sinônimo(s):

Anti-LA

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.43

fonte biológica

rabbit

Nível de qualidade

forma do anticorpo

diluted serum

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

liquid

não contém

preservative

reatividade da espécie (prevista por homologia)

all

fabricante/nome comercial

Calbiochem®

condição de armazenamento

OK to freeze
avoid repeated freeze/thaw cycles

Isotipo

IgG

Condições de expedição

wet ice

temperatura de armazenamento

−70°C

modificação pós-traducional do alvo

unmodified

Descrição geral

Rabbit polyclonal antibody supplied as diluted serum. Recognizes native lipoic acid and lipoic acid covalently attached to proteins.
Recognizes native lipoic acid. Does not recognize lipoic acid modified by 4-HNE (4-hydroxy-2-noneal) and other lipid peroxidation products.
This Anti-Lipoic Acid Rabbit pAb is validated for use in ELISA, Frozen Sections, Immunoblotting, Paraffin Sections for the detection of Lipoic Acid.

Imunogênio

lipoic acid conjugated to KLH

Aplicação

ELISA (1:500-1:1000)

Frozen Sections (1:50-1:500)

Immunoblotting (1:1000-1:10,000)

Paraffin Sections (1:50-1:500)

Advertência

Toxicity: Standard Handling (A)

forma física

serum diluted in buffer, 50% glycerol, pH 7.5.

Outras notas

Does not bind lipoic acid modified by 4-HNE (4-hydroxy-2-noneal) and other lipid peroxidation products. Useful for assessing whether protein-bound lipoic acids have undergone certain forms of oxidative modification. The presence of protein-bound lipoic acid can be used as a marker for mitochondria. Variables associated with assay conditions will dictate the optimal working dilution.
Sasaki, M., et al. 2000. J. Autoimmun.15, 51.
Heitzer, T., et al. 2001. Free Radic. Biol. Med.31, 53.
Patrick. L. 2000. Altern. Med. Rev.5, 290.
Shi, S.S., et al. 1999. Antioxid. Redox Signal1, 123.
Humphries, K.M. and Szeda, L.I. 1998. Biochemistry37, 15835.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1


Certificados de análise (COA)

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Methods in molecular biology (Clifton, N.J.), 372, 389-403 (2008-03-05)
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Malonyl-coenzyme A (malonyl-CoA) is a central metabolite in mammalian fatty acid biochemistry generated and utilized in the cytoplasm; however, little is known about noncanonical organelle-specific malonyl-CoA metabolism. Intramitochondrial malonyl-CoA is generated by a malonyl-CoA synthetase, ACSF3, which produces malonyl-CoA from malonate

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