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810253P

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dehydroergosterol (DHE)

ergosta-5,7,9(11),22-tetraen-3β-ol, powder

Sinônimo(s):

DHE

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About This Item

Fórmula empírica (Notação de Hill):
C28H42O
Número CAS:
516-85-8
Peso molecular:
394.63
Número MDL:
MFCD00083319
Código UNSPSC:
12352211
NACRES:
NA.25

R$ 457,00

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Ensaio

>99% (TLC)

Formulário

powder

embalagem

pkg of 1 × 1 mg (with stopper and crimp cap (810253P-1mg))

fabricante/nome comercial

Avanti Research™ - A Croda Brand 810253P

Condições de expedição

dry ice

temperatura de armazenamento

−70°C

cadeia de caracteres SMILES

O[C@H]1CC[C@]2(C(=CC=C3[C@H]4[C@@]([C@H](CC4)[C@H](C)\C=C\[C@@H](C(C)C)C)(CC=C32)C)C1)C

InChI

1S/C28H42O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,14,18-20,22,24-25,29H,11-13,15-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,27-,28+/m0/s1

chave InChI

QSVJYFLQYMVBDR-CMNOFMQQSA-N

Descrição geral

Dehydroergosterol (DHE) is a fluorescent sterol that possesses similar biophysical properties as cholesterol.[1][2] It is found in yeast cells and other fungi.[2]

Aplicação

Dehydroergosterol (DHE) is suitable for the transfer of DHE from a population of donor (LD) to acceptor (LA) liposomes.[3]

Ações bioquímicas/fisiológicas

Dehydroergosterol (DHE) is used for the visualization of intracellular traffic and intracellular transport kinetics.[1][2]

Embalagem

2 mL Amber Serum Vial with Stopper and Crimp Cap (810253P-1mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number

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Molecular basis for sterol transport by StART-like lipid transfer domains
Horenkamp FA, et al.
The Embo Journal, 37(6) (2018)
Reynold Homan et al.
Analytical biochemistry, 441(1), 80-86 (2013-07-16)
We describe a simple but sensitive fluorescence method to accurately detect the esterification activity of lecithin:cholesterol acyltransferase (LCAT). The new assay protocol employs a convenient mix, incubate, and measure scheme. This is possible by using the fluorescent sterol dehydroergosterol (DHE)
Mohsen Pourmousa et al.
The journal of physical chemistry. B, 118(26), 7345-7357 (2014-06-04)
Although dehydroergosterol (DHE) is one of the most commonly used cholesterol (CHOL) reporters, it has remained unclear why it performs well compared with most other CHOL analogues and what its possible limitations are. We present a comprehensive study of the
Olav Garvik et al.
Chemistry and physics of lipids, 159(2), 114-118 (2009-05-30)
The fluorescent sterol dehydroergosterol (DHE) is often used as a marker for cholesterol in cellular studies. We show by vesicle fluctuation analysis that DHE has a lower ability than cholesterol to stiffen lipid bilayers suggesting less efficient packing with phospholipid
Daniel Wüstner et al.
Microscopy research and technique, 74(1), 92-108 (2010-12-25)
Dehydroergosterol (DHE) is an intrinsically fluorescent sterol with absorption/emission in the ultraviolet (UV) region and biophysical properties similar to those of cholesterol. We compared the potential of UV-sensitive low-light-level wide-field (UV-WF) imaging with that of multiphoton (MP) excitation microscopy to
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