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900617

Sigma-Aldrich

(4-(Hydroxymethyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone

≥95%

Sinônimo(s):

Hydroxyl benzophenone alkyne, Probe building block

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About This Item

Fórmula empírica (Notação de Hill):
C17H14O3
Número CAS:
1940176-39-5
Peso molecular:
266.29
Código UNSPSC:
12352200

Ensaio

≥95%

Formulário

powder or crystals

adequação da reação

reaction type: click chemistry

temperatura de armazenamento

−20°C

Aplicação

(4-(Hydroxymethyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Outras notas


Technology Spotlight: Trifuctional Probe Building Blocks

A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS

Development of Sulfonamide Photoaffinity Inhibitors for Probing Cellular γ-Secretase

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
MKCD2804
MKCC8937

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Artigos

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

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