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53838-U

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Ascentis® Express 90Å C8 (2.7 μm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

Synonym(e):

Core-shell (SPP) Fused Core C8 HPLC column

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About This Item

UNSPSC-Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Ascentis® Express C8, 2,7 μm HPLC-Säule, 2.7 μm particle size, L × I.D. 15 cm × 4.6 mm

Materialien

stainless steel column

Agentur

suitable for USP L7

Produktlinie

Ascentis®

Leistungsmerkmale

endcapped

Hersteller/Markenname

Ascentis®

Verpackung

1 ea of

Parameter

60 °C temp. range
600 bar max. pressure (9000 psi)

Methode(n)

HPLC: suitable
LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable

L × ID

15 cm × 4.6 mm

Oberflächenbereich

135 m2/g

Verunreinigungen

<5 ppm metals

Matrix

Fused-Core particle platform
superficially porous particle

Aktive Matrixgruppe

C8 (octyl) phase

Partikelgröße

2.7 μm

Porengröße

90 Å

operating pH range

2-9

Anwendung(en)

food and beverages

Trenntechnik

reversed phase

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Allgemeine Beschreibung

Ascentis Express HPLC-Säulen bieten durch Fused-Core® Partikeltechnologie die hohe Geschwindigkeit und Effizienz von Partikeln mit weniger als 2 μm Durchmesser, wobei gleichzeitig ein geringer Rückdruck beibehalten wird. Anwender der UPLC® (oder anderer Ultrahochdrucksysteme) und der konventionellen HPLC profitieren von dieser Kombination aus hoher Effizienz und geringem Rückdruck.
Bitte besuchen Sie die Ascentis Express Homepage, um weitere Informationen über diese neue Säulentechnologie zu erhalten.

Anwendung


  • Recent trends in ultra-fast HPLC: new generation superficially porous silica columns.: This review explores the evolution and performance of superficially porous silica columns in high-performance liquid chromatography (HPLC), including those similar to the Ascentis Express C8, 2.7 μm. The focus is on the technology′s impact on enhancing analytical speed and efficiency (Ali et al., 2012).

  • Development and validation of an HPLC-MS/MS method to determine clopidogrel in human plasma. Use of incurred samples to test back-conversion.: This study details the development of an HPLC-MS/MS analytical method using columns such as the Ascentis Express C8, 2.7 μm, aimed at quantifying clopidogrel in plasma, demonstrating the column′s utility in clinical pharmacokinetic assessments (Silvestro et al., 2010).

Rechtliche Hinweise

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.
UPLC is a registered trademark of Waters

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Lagerklassenschlüssel

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WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
USZB005730
USZB005729
USZB005728
USZB005727
USZB005726

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Ugandar Reddy Inugala et al.
Journal of chromatographic science, 51(5), 453-459 (2012-10-13)
This paper describes the development of a rapid, novel, stability-indicating gradient reversed-phase high-performance liquid chromatographic method and associated system suitability parameters for the analysis of naproxcinod in the presence of its related substances and degradents using a quality-by-design approach. All
Sreenivasa Rao Chitturi et al.
Journal of pharmaceutical and biomedical analysis, 55(1), 31-47 (2011-02-15)
This paper proposes a simple and selective RP-HPLC method for the determination of process impurities and degradation products (degradants) of atazanavir sulfate (ATV) drug substance. Chromatographic separation was achieved on Ascentis(®) Express C8, (150mm×4.6mm, 2.7μm) column thermostated at 30°C under
Luigi Silvestro et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(30), 3134-3142 (2010-10-20)
Quantitative methods using LC-MS/MS allow achievement of adequate sensitivity for pharmacokinetic studies with clopidogrel; three such methods, with LLOQs as low as 5 pg/mL, were developed and fully validated according to the well established FDA 2001 guidelines. The chromatographic separations
Han Young Eom et al.
Journal of chromatography. A, 1217(26), 4347-4354 (2010-05-11)
Saikosaponins are triterpene saponins derived from the roots of Bupleurum falcatum L. (Umbelliferae), which has been traditionally used to treat fever, inflammation, liver diseases, and nephritis. It is difficult to analyze saikosaponins using HPLC-UV due to the lack of chromophores.
Federica Pellati et al.
Journal of pharmaceutical and biomedical analysis, 81-82, 126-132 (2013-05-07)
A closed-vessel microwave-assisted extraction (MAE) technique was optimized for the first time for the extraction of polyphenols from raw propolis. The results obtained by means of response surface experimental design methodology showed that the best global response was reached when
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Ascentis® Express C8 U/HPLC Columns

When a C18 doesn′t give the desired separation, or your sample contains compounds that are known to be difficult to retain or resolve on a C18, consider changing to an Ascentis® Express C8 column.

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