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Merck

50392-U

Supelco

Ascentis® Express 90Å C8 (5 μm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

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About This Item

UNSPSC-Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Ascentis® Express C8, 5 μm HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm

Materialien

stainless steel column

Qualitätsniveau

Agentur

suitable for USP L7

Produktlinie

Ascentis®

Leistungsmerkmale

endcapped

Hersteller/Markenname

Ascentis®

Verpackung

1 ea of

Parameter

60 °C temp. range
600 bar max. pressure (9000 psi)

Methode(n)

HPLC: suitable
LC/MS: suitable

L × ID

15 cm × 4.6 mm

Oberflächenbereich

90 m2/g

Verunreinigungen

<5 ppm metals

Matrix

Fused-Core particle platform
superficially porous particle

Aktive Matrixgruppe

C8 (octyl) phase

Partikelgröße

5 μm

Porengröße

90 Å pore size

Betriebs-pH-Wert

2-9

Anwendung(en)

food and beverages

Trenntechnik

reversed phase

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Allgemeine Beschreibung

Ascentis® Express 5 μm C8 is a high-speed, high-performance liquid chromatography column based on the highly efficient Fused-Core® particle design. The Fused-Core particle provides a thin porous shell of high-purity silica surrounding a solid silica core. This particle design exhibits very high column efficiency due to the shallow diffusion paths in the 0.6-micron thick porous shell and the highly uniform overall particle size of 5-microns. The densely bonded, extensively endcapped dimethyloctyl stationary phase of Ascentis Express 5 μm C8 provides a stable, reversed-phase packing that can be used for basic, acidic, or neutral compounds.

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Rechtliche Hinweise

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Sreenivasa Rao Chitturi et al.
Journal of pharmaceutical and biomedical analysis, 55(1), 31-47 (2011-02-15)
This paper proposes a simple and selective RP-HPLC method for the determination of process impurities and degradation products (degradants) of atazanavir sulfate (ATV) drug substance. Chromatographic separation was achieved on Ascentis(®) Express C8, (150mm×4.6mm, 2.7μm) column thermostated at 30°C under
Ugandar Reddy Inugala et al.
Journal of chromatographic science, 51(5), 453-459 (2012-10-13)
This paper describes the development of a rapid, novel, stability-indicating gradient reversed-phase high-performance liquid chromatographic method and associated system suitability parameters for the analysis of naproxcinod in the presence of its related substances and degradents using a quality-by-design approach. All
Luigi Silvestro et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(30), 3134-3142 (2010-10-20)
Quantitative methods using LC-MS/MS allow achievement of adequate sensitivity for pharmacokinetic studies with clopidogrel; three such methods, with LLOQs as low as 5 pg/mL, were developed and fully validated according to the well established FDA 2001 guidelines. The chromatographic separations
Han Young Eom et al.
Journal of chromatography. A, 1217(26), 4347-4354 (2010-05-11)
Saikosaponins are triterpene saponins derived from the roots of Bupleurum falcatum L. (Umbelliferae), which has been traditionally used to treat fever, inflammation, liver diseases, and nephritis. It is difficult to analyze saikosaponins using HPLC-UV due to the lack of chromophores.
Federica Pellati et al.
Journal of pharmaceutical and biomedical analysis, 81-82, 126-132 (2013-05-07)
A closed-vessel microwave-assisted extraction (MAE) technique was optimized for the first time for the extraction of polyphenols from raw propolis. The results obtained by means of response surface experimental design methodology showed that the best global response was reached when

Artikel

HPLC-DAD method on Ascentis® Express C8 column analyzes safinamide purity and related impurities meeting system suitability criteria.

When a C18 doesn′t give the desired separation, or your sample contains compounds that are known to be difficult to retain or resolve on a C18, consider changing to an Ascentis® Express C8 column.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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