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P5084

Sigma-Aldrich

PTIO

Synonym(e):

2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide

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25 MG
€ 163,00
100 MG
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About This Item

Empirische Formel (Hill-System):
C13H17N2O2
CAS-Nummer:
18390-00-6
Molekulargewicht:
233.29
MDL-Nummer:
MFCD00059929
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329820215
NACRES:
NA.32

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Form

powder

Qualitätsniveau

200

Lagertemp.

2-8°C

SMILES String

CC1(C)N([O])C(c2ccccc2)=[N+]([O-])C1(C)C

InChI

1S/C13H17N2O2/c1-12(2)13(3,4)15(17)11(14(12)16)10-8-6-5-7-9-10/h5-9H,1-4H3

InChIKey

DYUUGILMVYJEHY-UHFFFAOYSA-N

Anwendung

2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIO) has been used as a nitric oxide (NO) scavenger.[1][2]

Biochem./physiol. Wirkung

2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIOs) derivatives react with nitric oxide (NO) to yield the corresponding imino nitroxides (PTIs) and nitrogen dioxide (NO2).[3]
A stable radical scavenger for nitric oxide; affects NO without affecting NO synthase; has significant inhibitory activity against NO biological actions.
Stable radical scavenger for nitric oxide without affecting NO synthase; inhibits NO activity.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
0000361858
0000277368
0000361858
0000308069
0000141139

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Victoria P A Johnstone et al.
Learning & memory (Cold Spring Harbor, N.Y.), 18(10), 625-633 (2011-09-22)
Long-term potentiation (LTP) is an important process underlying learning and memory in the brain. At CA3-CA1 synapses in the hippocampus, three discrete forms of LTP (LTP1, 2, and 3) can be differentiated on the basis of maintenance and induction mechanisms.
Ekaterina Minaeva et al.
PloS one, 12(10), e0186851-e0186851 (2017-10-20)
Truncated hemoglobins constitute a large family, present in bacteria, in archaea and in eukaryotes. However, a majority of physiological functions of these proteins remains to be elucidated. Identification and characterization of a novel role of truncated hemoglobins in the model
Moonhee Lee et al.
Brain research, 1400, 99-111 (2011-06-07)
Activated monocytes/macrophages are known to release toxic materials. Identification of these materials is important for developing more effective treatments for inflammatory disorders where self attack occurs. We stimulated human monocytes and THP-1 cells with LPS/IFNγ and measured the toxic effects
Nitric oxide is involved in methyl jasmonate-induced defense responses and secondary metabolism activities of Taxus cells.
Wang JW and Wu JY
Plant & Cell Physiology, 46(6), 923-930 (2005)
Luca G Mariotti et al.
International journal of radiation biology, 88(10), 751-762 (2012-06-20)
To investigate the mechanisms regulating the pathways of the bystander transmission in vitro, focusing on the radiation-perturbed signalling (via Interleukine 6, IL-6) of the irradiated cells after exposure to low doses of different radiation types. An integrated 'systems radiation biology'
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