523350

PTIO

≥98% (titration), Nitric oxide radical scavenger, solid

• Synonym(e): PTIO, 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide
• Empirische Formel (Hill-System): C₁₃H₁₇N₂O₂
• CAS-Nummer: 18390-00-6
• Molekulargewicht: 233.29
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD00059929
• Assay: ≥98% (titration)
• Form: solid
• Storage condition: OK to freeze

Eigenschaften

• Produktname: PTIO, Nitric oxide radical scavenger.
• Quality Segment: 100
• assay: ≥98% (titration)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: dark blue
• solubility: ethanol: soluble, water: soluble
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: [N+]1(=C([NH](=O)C(C1(C)C)(C)C)c2ccccc2)[O-]
• InChI: 1S/C13H17N2O2/c1-12(2)13(3,4)15(17)11(14(12)16)10-8-6-5-7-9-10/h5-9H,1-4H3
• InChI key: DYUUGILMVYJEHY-UHFFFAOYSA-N

Beschreibung

General description

Nitric oxide radical scavenger. Reacts with nitric oxide in a stoichiometric manner without affecting nitric oxide synthase activity. Inhibits the enhanced vascular permeability in solid tumors.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Nitric oxide radical scavenger

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.

Other Notes

Hogg, N., et al. 1995. Free Radic. Res. 22, 47.
Maeda, H., et al. 1994. Jpn. J. Cancer Res.85, 331.
Yoshida, M., et al. 1994. Biochem. Biophys. Res. Commun.202, 923.
Akaike, T., et al. 1993. Biochemistry32, 827.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable