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Wichtige Dokumente
M9940
Mercaptoethylguanidine hemisulfate salt
≥98%
Synonym(e):
MEG hemisulfate salt
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
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About This Item
Lineare Formel:
H2NC(=NH)NHSCH2CH3 · 1/2 H2SO4
CAS-Nummer:
Molekulargewicht:
168.23
MDL-Nummer:
UNSPSC-Code:
12352202
PubChem Substanz-ID:
NACRES:
NA.77
Empfohlene Produkte
Assay
≥98%
Form
solid
Versandbedingung
wet ice
Lagertemp.
2-8°C
SMILES String
OS(O)(=O)=O.NC(=N)NCCS.NC(=N)NCCS
InChI
1S/2C3H9N3S.H2O4S/c2*4-3(5)6-1-2-7;1-5(2,3)4/h2*7H,1-2H2,(H4,4,5,6);(H2,1,2,3,4)
InChIKey
XJKZAAUVINNNNC-UHFFFAOYSA-N
Anwendung
Selective iNOS inhibitor and scavenger of peroxynitrite.
Biochem./physiol. Wirkung
Demonstrates potent antiinflammatory effects in an animal model of airway infection that mimics human cystic fibrosis.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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M Kiroycheva et al.
Journal of the American Society of Nephrology : JASN, 11(6), 1026-1032 (2000-05-23)
Previous studies in beta(s) sickle cell mice demonstrated renal immunostaining for nitrotyrosine, which is putative evidence of peroxynitrite (ONOO(-)) formation. ONOO(-) is known to nitrate tyrosine residues of various enzymes, thereby interfering with phosphorylation and inactivating them. The present study
Mustafa Ozturk et al.
Journal of pineal research, 50(1), 89-96 (2010-11-11)
Doxorubicin (DOX) and Trastuzumab (TRAST) are effective agents for the treatment of many neoplastic diseases. Cardiotoxicity is a major side effect of these drugs and limit their use. In this study, the possible protective effects of melatonin (MEL), mercaptoethylguanidine (MEG)
K Soejima et al.
American journal of respiratory and critical care medicine, 163(3 Pt 1), 745-752 (2001-03-20)
Patients with severe burn and/or smoke inhalation injury suffer both systemic and pulmonary vascular hyperpermeability. We hypothesized that nitric oxide (NO) produced by inducible nitric oxide synthase (iNOS) plays a role in the changes in microvascular permeability seen with this
The effect of inducible nitric oxide synthase (iNOS) inhibition on smoke inhalation injury in sheep.
K Soejima et al.
Shock (Augusta, Ga.), 13(4), 261-266 (2000-04-25)
Recent studies on smoke inhalation injury have been focused on nitric oxide (NO) as an essential factor of progressive lung injury. We studied the effects of inducible nitric oxide synthase (iNOS) inhibition on inhalation injury in sheep. Sheep (n =
Christian Kellner et al.
Cancer letters, 215(1), 43-52 (2004-09-18)
We investigated the early events involved in loss of mitochondrial membrane potential (DeltaPsi(mt)) leading to apoptosis in cells derived from patients with acute lymphocytic leukemia after exposure to phenolic antioxidants. Using the nitric oxide binding dye diaminofluorescein-FM diacetate, we found
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