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Merck

T7511

Supelco

Tripelennamin -hydrochlorid

analytical standard

Synonym(e):

2-[Benzyl-(2-dimethylaminoethyl)-amino]-pyridin, N-Benzyl-N′,N′-dimethyl-N-(2-pyridyl)-ethylendiamin -hydrochlorid, Pyribenzamin -hydrochlorid

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25 G
€ 95,60

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25 G
€ 95,60

About This Item

Empirische Formel (Hill-System):
C16H21N3 · HCl
CAS-Nummer:
Molekulargewicht:
291.82
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

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Qualität

analytical standard

Qualitätsniveau

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary

Format

neat

SMILES String

CN(C)CCN(CC1=CC=CC=C1)C2=NC=CC=C2.Cl

InChI

1S/C16H21N3.ClH/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15;/h3-11H,12-14H2,1-2H3;1H

InChIKey

FSSICIQKZGUEAE-UHFFFAOYSA-N

Angaben zum Gen

human ... HRH1(3269)

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Allgemeine Beschreibung

Tripelennamine hydrochloride is an antihistamine drug, which is used in the treatment of bronchitis, asthma and bronchoconstriction.[1]

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tripelennamine hydrochloride may be used as a reference standard in the determination of tripelennamine hydrochloride in samples of animal feed by gas chromatography (GC) method, wastewater and urine using high performance liquid chromatography (HPLC) method employing fluorescence detector.[1]

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Die Dokumentenbibliothek aufrufen

Trace determination of the antihistamines tripelennamine hydrochloride, thenyldiamine hydrochloride, and chlorothen citrate in admixture in animal feed, human urine, and wastewater by high-pressure liquid chromatography and use of a fluorescence detector.
Thompson TH, et al.
Talanta, 30(4), 251-260 (1983)
Y Xia et al.
European journal of pharmacology, 316(1), 81-85 (1996-11-28)
Effects of histamine and related agonists and antagonists on formation of cAMP were determined for enzymatically dissociated ganglia from the myenteric plexus of the guinea-pig small intestine. Formation of cAMP was stimulated by histamine in both dose- and time-dependent manners.
C E Johanson et al.
Psychopharmacology, 126(2), 140-146 (1996-07-01)
Twenty volunteers were trained to discriminate between 75 mg tripelennamine (TP) and placebo. During the first four sessions, the drugs were identified prior to ingestion by letter code. During the next six sessions, the procedure was the same except the
G Viola et al.
Die Pharmazie, 59(12), 948-951 (2005-01-11)
The influence of mast cell activation on the secretion of prolactin has been studied in rats receiving lysophosphatidylserine, a natural occurring phospholipid with secretagogue activity in these cells. After the i.v. injection of lysophosphatidylserine (10 mg/kg) a plasma prolactin peak
S Sekizawa et al.
Respiration physiology, 112(1), 13-22 (1998-08-08)
The response to histamine of nasal afferents has been studied in guinea pigs by recording the electrical activity of the whole ethmoidal nerve (EN) or that of single units. Guinea pigs were anaesthetized with urethane and breathed through a tracheostomy.

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