8.20112

Anthranilic acid

for synthesis

• Synonym(e): Anthranilic acid, 2-Aminobenzoic acid
• Lineare Formel: 2-(NH₂)C₆H₄COOH
• CAS-Nummer: 118-92-3
• Molekulargewicht: 137.14
• UNSPSC Code: 12352106
• EC Index Number: 204-287-5
• NACRES: NA.22
• MDL number: MFCD00007712
• Assay: ≥99.0% (acidimetric)
• Form: solid
• Grade: synthesis grade

Eigenschaften

• grade: synthesis grade
• Quality Segment: 200
• vapor pressure: 0.001 hPa ( 52.6 °C)
• assay: ≥99.0% (acidimetric)
• form: solid
• autoignition temp.: >530 °C
• potency: 4550 mg/kg LD₅₀, oral (Rat)
• mp: 146-148 °C
• transition temp: flash point 150 °C
• solubility: 4.5 g/L
• density: 1.383 g/cm³ at 23 °C
• bulk density: 500 kg/m³
• storage temp.: 2-30°C
• SMILES string: Nc1c(cccc1)C(=O)O
• InChI: 1S/C7H7NO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H,9,10)
• InChI key: RWZYAGGXGHYGMB-UHFFFAOYSA-N

Beschreibung

Application

• Anthranilic acid in bio-imaging: Anthranilic acid produced by Virgibacillus salarius MML1918 was characterized for its potential in bio-imaging applications, demonstrating utility in visualizing biological processes (Nandhagopal and Narayanasamy, 2024).


• Anthranilic acid as a metabolite biomarker: A study utilized targeted metabolomics to identify anthranilic acid as a biomarker in Salmonella enteritidis-contaminated chickens, enhancing detection and safety measures in food chemistry (Chen et al., 2023).


• Anthranilic acid in metabolic pathway analysis: A comparative study on the kynurenine pathway in cell lines incorporated anthranilic acid, utilizing LC-MS/MS-based targeted metabolomics to explore selective inhibition of indoleamine and tryptophan 2,3-dioxygenases (Villani et al., 2024).


• Anthranilic acid in quantitative metabolomics: Liquid chromatography-tandem mass spectrometry was used for the simultaneous quantification of tryptophan, serotonin, and kynurenine pathway metabolites, including anthranilic acid, in various biological samples, aiding in comprehensive metabolic profiling (Frobel et al., 2023).

Analysis Note

Assay (acidimetric): ≥ 99.0 %
Melting range (lower value): ≥ 144 °C
Melting range (upper value): ≤ 147 °C
Identity (IR): passes test

Sicherheitshinweise

• pictograms: GHS05
• signalword: Danger
• hcodes: H318
• pcodes: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: 302.0 °F - closed cup
• flash_point_c: 150 °C - closed cup