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452483

Sigma-Aldrich

1-Methyl-D-tryptophan

95%, for peptide synthesis

Synonym(e):

(2R)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, D-(+)-1-Methyltryptophan

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250 MG
€ 44,40
1 G
€ 130,00
10 G
€ 944,00

€ 44,40


Voraussichtliches Versanddatum10. April 2025


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250 MG
€ 44,40
1 G
€ 130,00
10 G
€ 944,00

About This Item

Empirische Formel (Hill-System):
C12H14N2O2
CAS-Nummer:
Molekulargewicht:
218.25
MDL-Nummer:
UNSPSC-Code:
12352209
PubChem Substanz-ID:
NACRES:
NA.22

€ 44,40


Voraussichtliches Versanddatum10. April 2025


Bulk-Bestellung anfordern

Produktbezeichnung

1-Methyl-D-tryptophan, 95%

Qualitätsniveau

Assay

95%

Form

lumps and powder

Optische Aktivität

[α]22/D +12.4°, c = 2 in acetic acid

Eignung der Reaktion

reaction type: solution phase peptide synthesis

mp (Schmelzpunkt)

242-245 °C (lit.)

Anwendung(en)

peptide synthesis

SMILES String

Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12

InChI

1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m1/s1

InChIKey

ZADWXFSZEAPBJS-SNVBAGLBSA-N

Anwendung

Used to prepare a number of natural products including macroline alkaloids using the Pictet-Spengler reaction of tryptophan esters with aldehydes[1] also used in the synthesis of 1-substituted indolactam precursors.[2]

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Questions

1–5 of 5 Questions  
  1. I have a question regarding 1-methyl-D-tryptophan (452483). Is this suitable for cell culture study purpose? Thank you.

    1 answer
    1. This product is listed as suitable for peptide synthesis. It may be okay for cell culture, but it is not tested with that application in mind, so the suitability would need to be determined by the end user. What is tested can be found on the product COA, an example of which can be found in the 'Documentation' section of the product page.

      Helpful?

  2. How should Product 452483, 1-Methyl-D-tryptophan, be stored?

    1 answer
    1. This material is stable at room temperature without any special handling precautions.

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  3. What is Product 452483, 1-Methyl-D-tryptophan, soluble in?

    1 answer
    1. While we don't test the solubility of this product directly, we do have to dissolve it in acetic acid in order to test the optical rotation. We would also expect this to be soluble in a dilute hydrochloric acid solution (50mg/mL in 5N HCl). Both heat and sonication may be required in order to prepare a homogenous solution. Also, based on our experience with the DL (Product No. 860646) and L (Product No. 447439) forms, we would expect that dilute sodium hydroxide would also be a potential solvent (1g/100mL of 1M NaOH).

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  4. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  5. What is the solution stability of Product 452483, 1-Methyl-D-tryptophan?

    1 answer
    1. Unfortunately, we do not perform solution stability testing on this item or have experience with storing tryptophan solutions, so we would recommend making a fresh batch with each use.

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