Direkt zum Inhalt
Merck

HTR1B

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

Synonyme:
5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
Spezies:
Human HTR1B (3351), Mouse Htr1b (15551), Rat Htr1b (25075), chicken HTR1B (421858), Zebrafish htr1b (561647), dog HTR1B (403741), cow HTR1B (317707), Horse HTR1B (100009680), domestic cat HTR1B (100144391), Domestic Rabbit HTR1B (100009594) ...Mehr
UniProtKB-ID:
P28222, Q4VAY7
Gen-ID:
  • Human(3351) Summary: The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]
  • Mouse(15551) 5-hydroxytryptamine (serotonin) receptor 1B
  • Rat(25075) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • chicken(421858) 5-hydroxytryptamine (serotonin) receptor 1B
  • Zebrafish(561647) 5-hydroxytryptamine (serotonin) receptor 1B
  • dog(403741) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • cow(317707) 5-hydroxytryptamine (serotonin) receptor 1B
  • Horse(100009680) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic cat(100144391) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • Domestic Rabbit(100009594) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • sheep(101111375) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic guinea pig(100135543) 5-hydroxytryptamine (serotonin) receptor 1B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
S1198
Sumatriptan-Succinat, ≥98% (HPLC), solid,
Spezies
human
SML0248
Zolmitriptan, ≥98% (HPLC),
Spezies
human
1457469
Naratriptan -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
1286413
Frovatriptansuccinat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
1642201
Sumatriptan-Succinat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
D9190
DCEBIO, ≥98% (HPLC), solid,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
G5793
GR 127935 hydrochloride hydrate, >98% (HPLC), powder,
Spezies
human
M149
Methiothepin mesylate salt, ≥98% (HPLC), solid,
Spezies
human
T6154
Trazodon -hydrochlorid, ≥99% (HPLC), powder,
Spezies
human
P8688
(S)-(−)-Propranolol -hydrochlorid, ≥98% (TLC), powder,
Spezies
human
M137
Methysergid -maleat (Salz), solid,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
SAB4501470
Anti-5-HT-1B antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence
immunohistochemistry
SAB4501471
Anti-HTR1B antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence
western blot
SAB2500924
Anti-Serotonin Receptor 1B/HTR1B antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
canine, human, mouse, rat
Anwendung
ELISA
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
T6154
Trazodon -hydrochlorid, ≥99% (HPLC), powder,
Spezies
human
P8688
(S)-(−)-Propranolol -hydrochlorid, ≥98% (TLC), powder,
Spezies
human
T3146
Trimipramin -maleat (Salz), ≥98% (TLC), powder,
Spezies
human
Z101
Zimelidin -dihydrochlorid, solid,
Spezies
human

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
T6154
Trazodon -hydrochlorid, ≥99% (HPLC), powder,
Spezies
human
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Spezies
human
F1678
R-(−)-Fluoxetin -hydrochlorid, >98% (HPLC), solid,
Spezies
human
F132
Fluoxetin -hydrochlorid, solid,
Spezies
human
R0875
Reserpin, ,
Spezies
human

Small Molecule - Ligand

Produktnummer
Beschreibung
Spezies
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Spezies
human

Small Molecule - Metabolite

Produktnummer
Beschreibung
Spezies
H8876
5-Hydroxyindol-3-Essigsäure, ≥98% (HPLC), crystalline,
Spezies
human

Small Molecule - Precursor

Produktnummer
Beschreibung
Spezies
H9772
5-Hydroxy-L-Tryptophan, powder,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
EMU044151
MISSION® esiRNA, targeting mouse Htr1b,
Spezies
mouse