T3146

Trimipramin -maleat (Salz)

≥98% (TLC), serotonin transport blocker, powder

• Empirische Formel (Hill-System): C₂₀H₂₆N₂ · C₄H₄O₄
• CAS-Nummer: 521-78-8
• Molekulargewicht: 410.51
• NACRES: NA.77
• PubChem Substance ID: 24278731
• UNSPSC Code: 12352116
• EC Number: 208-318-3
• MDL number: MFCD00082376
• Assay: ≥98% (TLC)
• Form: powder

Eigenschaften

• Produktname: Trimipramin -maleat (Salz), ≥98% (TLC), powder
• Quality Segment: 200
• assay: ≥98% (TLC)
• form: powder
• color: white to off-white
• solubility: chloroform: soluble 50 mg/ml, clear, colorless to faintly yellow
• originator: Sanofi Aventis
• storage temp.: 2-8°C
• SMILES string: OC(=O)\C=C\C(O)=O.CC(CN(C)C)CN1c2ccccc2CCc3ccccc13
• InChI: 1S/C20H26N2.C4H4O4/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22;5-3(6)1-2-4(7)8/h4-11,16H,12-15H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
• InChI key: YDGHCKHAXOUQOS-WLHGVMLRSA-N
• Gene Information: human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

Beschreibung

Application

Trimipramine maleate has been used to develop chiral separation methods using capillary electrophoresis⁴.

Biochem/physiol Actions

Antidepressant; serotonin transport blocker that also blocks norepinephrine uptake.

Preparation Note

Trimipramine maleate is soluble in chloroform at 50 mg/ml to yield a clear, colorless to faint yellow solution.

Sicherheitshinweise

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335,H361
• pcodes: P202 - P261 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges