QBD10009

Biotin-dPEG^®₄-TFP ester

• 同義詞: Polyethylene glycol
• 經驗公式（希爾表示法）: C₂₇H₃₇F₄N₃O₈S
• 分子量：: 639.66
• 分類程式碼代碼: 12352108
• PubChem物質ID: 329823873
• NACRES: NA.22

屬性

• 化驗: >90%
• 形狀: solid or viscous liquid
• 反應適用性: reaction type: Biotinylations; reaction type: Biotinylations; reactivity: amine reactive; reagent type: cross-linking reagent
• 聚合物結構: shape: linear; functionality: monofunctional
• 運輸包裝: ambient
• 儲存溫度: −20°C
• SMILES 字串: O=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O
• InChI 密鑰: XBGOXOZYGAXNFP-UHFFFAOYSA-N

描述

應用

Biotin-dPEG^®₄-TFP ester is an amphiphilic and hydrolytically stable compound used as a cross-linking reagent in biotinylations reactions.[1]

特點和優勢

Biotin-dPEG^®₄-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety which hydrolyzes more slowly than NHS ester in aqueous media and are more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG^®₄-TFP ester has a long spacer of precise length (19.2 Å) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. The PEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

法律資訊

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable