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RES6003H-B7

SAFC

HEPES

Synonim(y):

4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid, N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid)

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About This Item

Wzór empiryczny (zapis Hilla):
C8H18N2O4S
Numer CAS:
7365-45-9
Masa cząsteczkowa:
238.30
Beilstein:
883043
Numer WE:
230-907-9
Numer MDL:
MFCD00006158
Kod UNSPSC:
12161700
NACRES:
NA.21

pochodzenie biologiczne

synthetic

Postać

powder

metody

cell culture | mammalian: suitable

zanieczyszczenia

Endotoxin, microbial, and trace metals; tested

pH

4.7-5.3 (, )

przydatny zakres pH

6.8-8.2

pKa (25°C)

7.5

przydatność

suitable for manufacturing use

obecność zanieczyszczeń

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

ciąg SMILES

OCCN1CCN(CC1)CCS(O)(=O)=O

InChI

1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)

Klucz InChI

JKMHFZQWWAIEOD-UHFFFAOYSA-N

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Opis ogólny

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Zastosowanie

HEPES is a biological buffer often referred to as a “Good′s” buffer. It is the most commonly used biological buffer since the pKa of HEPES is 7.31 which corresponds to the physiological pH of 7.36. HEPES is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

HEPES is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream) and diagnostic reagents. HEPES based buffers are used in purification bioprocesses of antibodies, bioactives, proteins and growth factors.

Opakowanie

This product is available in the following package sizes:
RES6003H-B701X: 100g container
RES6003H-B703X: 5kg container
RES6003H-B705X: 25kg container
RES6003H-B706X: 50kg container

Informacje prawne

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

zastąpiony przez

Numer produktu
Opis
Cennik

137264

HEPES, EMPROVE® EVOLVE

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

P Dey et al.
Oncogene, 33(33), 4213-4225 (2013-10-01)
Estrogen receptor β (ERβ) is emerging as a critical factor in understanding prostate cancer biology. Although reduced in prostate cancer above Gleason grade 3, ERβ is a potential drug target at the initial stage of the disease. In human prostate
Frédéric Perros et al.
Journal of the American College of Cardiology, 65(7), 668-680 (2015-02-14)
Endothelial cell (EC) dysfunction plays a central role in the pathogenesis of pulmonary arterial hypertension (PAH), promoting vasoconstriction, smooth muscle proliferation, and inflammation. This study sought to test the hypothesis that nebivolol, a β1-antagonist and β2,3-agonist, may improve PAH and
Brendan M Leung et al.
Journal of tissue engineering and regenerative medicine, 9(11), 1247-1258 (2013-03-19)
Modular cardiac tissues developed both vascular and cardiac structures in vivo, provided that the host response was attenuated by omitting xenoproteins from the modules. Collagen gel modules (with Matrigel(TM)) containing cardiomyocytes (CMs) alone or CMs with surface-seeded endothelial cells (ECs; CM/EC
Alexandre Albanese et al.
ACS nano, 8(6), 5515-5526 (2014-05-07)
A nanoparticle's physical and chemical properties at the time of cell contact will determine the ensuing cellular response. Aggregation and the formation of a protein corona in the extracellular environment will alter nanoparticle size, shape, and surface properties, giving it
Suganthi Chittaranjan et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 20(12), 3159-3173 (2014-04-12)
Triple-negative breast cancers (TNBC) are defined by a lack of expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (ERBB2/HER2). Although initially responsive to chemotherapy, most recurrent TNBCs develop resistance, resulting in disease progression.
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