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Merck

MAK036

Sigma-Aldrich

Hemin Assay Kit

sufficient for 100 colorimetric tests

Synonim(y):

Hemin Quantitative Test Kit

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About This Item

Kod UNSPSC:
12161503
NACRES:
NA.84

zastosowanie

sufficient for 100 colorimetric tests

Zastosowanie

cosmetics
food and beverages

metoda wykrywania

colorimetric

powiązane choroby

immunological diseases; rheumatological diseases; gastrointestinal diseases; cardiovascular diseases

temp. przechowywania

2-8°C

Opis ogólny

Hemin, the oxidized version of heme, is an iron-containing prosthetic group for a diverse group of proteins. Free heme, which can be released from hemoglobin following hemolysis, is pro-inflammatory and contributes to iron-derived reactive oxygen species. Free hemin levels may be upregulated in various pathological conditions and can contribute to various inflammatory conditions including vascular disorders, renal failure, and immune-mediated disorders.

Zastosowanie

Hemin Assay Kit has been used to determine the level of free hemin (oxidized heme).

Przydatność

Suitable for use with cell and tissue culture supernatants, urine, plasma, serum, fecal material, media, and other biological fluids.

Zasada

In this assay, Hemin concentration is determined by a coupled enzyme reaction, which results in a colorimetric (570 nm) product, proportional to the Hemin present.
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Piktogramy

Health hazard

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

Zwroty wskazujące środki ostrożności

Klasyfikacja zagrożeń

Resp. Sens. 1

Kod klasy składowania

10 - Combustible liquids

Temperatura zapłonu (°F)

188.6 °F - closed cup

Temperatura zapłonu (°C)

87 °C - closed cup


Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Characterization of novel inhibition of indoleamine 2, 3-dioxygenase by targeting its apo form.
Ortiz-Meoz R F, et al.
bioRxiv, 324947-324947 (2018)
Laura Casares et al.
Redox biology, 28, 101321-101321 (2019-09-14)
Cannabidiol (CBD) is a major non-psychotropic phytocannabinoid that attracted a great attention for its therapeutic potential against different pathologies including skin diseases. However, although the efficacy in preclinical models and the clinical benefits of CBD in humans have been extensively
Kelly A Fader et al.
Toxicology and applied pharmacology, 321, 1-17 (2017-02-19)
Persistent aryl hydrocarbon receptor (AhR) agonists elicit dose-dependent hepatic lipid accumulation, oxidative stress, inflammation, and fibrosis in mice. Iron (Fe) promotes AhR-mediated oxidative stress by catalyzing reactive oxygen species (ROS) production. To further characterize the role of Fe in AhR-mediated
Guangjian Yang et al.
Open life sciences, 16(1), 930-936 (2021-09-24)
Immunoglobulin γ-1 heavy chain constant region (IGHG1) is a functional isoform of immunoglobulins and plays an important role in the cytolytic activity of immune effector cells. Dysregulated IGHG1 was implicated in the occurrence and development of various tumors. Protoporphyrin IX
Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBα/β activation in aryl hydrocarbon receptor-elicited hepatotoxicity.
Fader K A, et al.
Toxicology and Applied Pharmacology, 321, 1-17 (2017)

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