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AP130P

Sigma-Aldrich

Goat Anti-Mouse IgG & IgM Antibody, HRP conjugate

0.8 mg/mL, Chemicon®

Synonim(y):

Goat Anti-Mouse IgG Antibody

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About This Item

Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.46

pochodzenie biologiczne

goat

Poziom jakości

białko sprzężone

peroxidase conjugate

forma przeciwciała

F(ab′)2 fragment of affinity isolated antibody

rodzaj przeciwciała

secondary antibodies

klon

polyclonal

reaktywność gatunkowa

mouse

producent / nazwa handlowa

Chemicon®

stężenie

0.8 mg/mL

metody

ELISA: suitable
western blot: suitable

Warunki transportu

wet ice

docelowa modyfikacja potranslacyjna

unmodified

Opis ogólny

Immunoglobulin G (IgG) is the most abundant immunoglobulin in the human serum. IgM constitutes 5-10% of total serum immunoglobulins. These immunoglobulins comprise four polypeptide chains with two heavy (H) chains and two light (L) chains. These polypeptide chains are inter-linked by disulfide bonds. IgM is a highly conserved antibody in vertebrates. IgM exists as a pentamer. Both IgG and IgM are secreted by B cells.

Zastosowanie

Goat Anti-Mouse IgG & IgM Antibody, HRP conjugate has been used in western blotting(1:400) and immunofluorescence (1:500)

Działania biochem./fizjol.

IgG facilitates antibody-dependent cell-mediated cytotoxicity (ADCC). It also aids in the activation of the classical pathway of the complement system. IgG neutralizes virus particles and toxins. IgM, an antibody that is expressed early during an immune response, aids in engulfing apoptotic cells. It exhibits polyreactive and autoreactive functionality. IgM induces tissue homeostasis by mediating the clearance of tissue-based molecules. Lower levels of IgM in serum are associated with increased autoimmune response and a higher risk of developing infections.

Informacje prawne

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Kod klasy składowania

13 - Non Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


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Odwiedź Bibliotekę dokumentów

Bojana Mirković et al.
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Chapter 12 - Immunoglobulin Titers and Immunoglobulin Subtypes
Gleason CA and Devaskar SU
Acanthamoeba: Biology and Pathogenesis (2011)
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Neurobiology of disease, 68, 1-15 (2014-04-22)
The misfolding and aggregation of α-synuclein (aSyn) eventually lead to an accumulation of toxic forms that disturb normal neuronal function and result in cell death. aSyn rich inclusions are seen in Parkinson's disease, dementia with Lewy bodies and other synucleinopathies.
Candida J Rebello et al.
Obesity (Silver Spring, Md.), 27(1), 103-111 (2018-12-07)
Naringenin, a citrus flavonoid, prevents diet-induced weight gain and improves glucose and lipid metabolism in rodents. There is evidence that naringenin activates brown fat and increases energy expenditure in mice, but little is known about its effects in humans. The
Erich Stefan et al.
eLife, 10 (2021-05-01)
ATP-binding cassette (ABC) transporters constitute the largest family of primary active transporters involved in a multitude of physiological processes and human diseases. Despite considerable efforts, it remains unclear how ABC transporters harness the chemical energy of ATP to drive substrate

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