5.00112

Cocarboxylase chloride

thiamine diphosphoric acid ester chloride EMPROVE^® API

• Synonim(y): Cocarboxylase chloride, Thiaminium diphosphoric acid ester chloride, Thiaminium pyrophosphate chloride, Thiaminium pyrophosphoric acid ester chloride, TPP
• Numer CAS: 154-87-0
• Masa cząsteczkowa: 460.77
• Numer MDL: MFCD00038740
• Kod UNSPSC: 12352107
• Numer indeksu EC: 205-836-1

Właściwości

• Poziom jakości: 600
• linia produktu: EMPROVE^® API
• Postać: solid
• pH: 1.0-1.4 (20 °C, 100 g/L in H₂O)
• mp: 240-244 °C (decomposition)
• rozpuszczalność: 220 g/L
• gęstość nasypowa: 500 kg/m³
• Zastosowanie: liquid formulation; pharmaceutical; semi-solid formulation; solid formulation
• temp. przechowywania: 2-25°C
• InChI: 1S/C12H18N4O7P2S.ClH/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);1H
• Klucz InChI: YXVCLPJQTZXJLH-UHFFFAOYSA-N

Opis

Opis ogólny

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Zastosowanie

Cocarboxylase chloride Emprove^® API is a source for Vitamin B1 for use in clinical nutrition, vitamin supplements and infusion for Vitamin B1 deficiency. Cocarboxylase Chloride (thiamine diphosphoric acid ester chloride) Emprove^® API is manufactured according to ICH Q7 guidelines. An ASMF is available.

Informacje prawne

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H317
• Zwroty wskazujące środki ostrożności: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Klasyfikacja zagrożeń: Skin Sens. 1
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable