914169
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) dimethacrylate
average Mn ~12,500
Synonim(y):
PEG-PPG-PEG, Pluronic Dimethacrylate, Pluronic F-127 dimethacrylate
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About This Item
Wzór liniowy:
C4H5O[C2H4O]x[C3H6O]y[C2H4O]zC4H5O2
Kod UNSPSC:
12162002
NACRES:
NA.23
Polecane produkty
Postać
powder
Poziom jakości
masa cząsteczkowa
average Mn ~12,500
kolor
off-white to yellow
temp. przechowywania
−20°C
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Zastosowanie
Poloxamers are nonionic, triblock copolymers containg a central hydrophobic chain of poly(propylene glycol) (PPG) and two terminal hydrophilic chains of poly(ethylene glycol) (PEG). Due to their amphiphilic structure, poloxamer solutions feature temperature dependent self-assembling and thermo-gelling behavior. Concentrated aqueous solutions of poloxamers are liquid at low temperature and form a gel at higher temperature, in a reversible process. This characteristic has allowed for these materials to be used as drug carriers for most routes of administration including oral, topical, intranasal, ocular, and parenteral. Methacrylate-modified derivatives are most commonly used as thermosensitive hydrogels for drug delivery and 3D bioprinting applications. After casting or printing, the material can be crosslinked to preserve the hydrogel structure.
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Photopolymerization of Pluronic F127 diacrylate: a colloid-templated polymerization.
Biase M D, et al.
Soft Materials, 7, 4928-4937 (2011)
Self-Assembly of Pluronic F127 Diacrylate in Ethylammonium Nitrate: Structure, Rheology, and Ionic Conductivity before and after Photo-Cross-Linking.
Barron C R L, et al.
Macromolecules, 49(14), 5179-5189 (2016)
J J Escobar-Chávez et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 9(3), 339-358 (2007-01-09)
It is, sometimes, desirable to maintain a constant plasma drug concentration within the therapeutically effective concentration range. The use of high viscosity hydromiscible vehicles such as hydrophilic gels, is one of various approaches for controlled drug delivery, and represents an
Christopher J Hansen et al.
Advanced materials (Deerfield Beach, Fla.), 25(1), 96-102 (2012-10-31)
Microvascular multinozzle arrays are designed and fabricated for high-throughput printing of functional materials. Ink-flow uniformity within these multigeneration, bifurcating microchannel arrays is characterized by computer modeling and microscopic particle image velocimetry (micro-PIV) measurements. Both single and dual multinozzle printheads are
Photopolymerization of Pluronic F127 diacrylate: a colloid-templated polymerization.
Manuela D B, et al.
Soft Materials, 7, 4928-4937 (2011)
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