MAPK14
mitogen-activated protein kinase 14
Synonimy:
CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA
Gatunek:
Human MAPK14 (1432), Mouse Mapk14 (26416), Rat Mapk14 (81649), naked mole-rat Mapk14 (101715692), domestic guinea pig Mapk14 (100723285), chicken MAPK14 (421183), Horse MAPK14 (100063532), dog MAPK14 (403856), domestic cat MAPK14 (101101135), Domestic Rabbit MAPK14 (100341695) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(1432) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(26416) mitogen-activated protein kinase 14
- Rat(81649) mitogen activated protein kinase 14
- naked mole-rat(101715692) mitogen-activated protein kinase 14
- domestic guinea pig(100723285) mitogen-activated protein kinase 14
- chicken(421183) mitogen-activated protein kinase 14
- Horse(100063532) mitogen-activated protein kinase 14
- dog(403856) mitogen-activated protein kinase 14
- domestic cat(101101135) mitogen-activated protein kinase 14
- Domestic Rabbit(100341695) mitogen-activated protein kinase 14
- sheep(100217411) mitogen-activated protein kinase 14
- cow(534492) mitogen-activated protein kinase 14
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ELISA
Numer produktu
Opis
Gatunek
Phospho-p38 α (pThr180 / pTyr182) ELISA Kit, fore detection of phospho-p38 alpha (pThr180 / pTyr182) in human or mouse cell and tissue lysates,
Gatunek
human
Phospho-p38 α (pThr180 / pTyr182) and pan-p38 ELISA Kit, for detection of phospho-p38 alpha (pThr180 / pTyr182) and pan-p38 in human or mouse cell and tissue lysates,
Gatunek
human
Cell-Based ELISA for detecting phospho-P38 MAPK (pThr180 / pTyr182) in cultured cell lines, 96 assays,
Gatunek
human
Cell-Based ELISA Sampler Kit for detecting phospho-ERK1/2 (pThr202/pTyr204), phospho-JNK (pThr183/pTyr185), and phospho-p38 MAPK (pThr180/pTyr182) in cultured cell lines, 192 assays,
Gatunek
rat, human, mouse
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-p38 MAPK (pThr179+Tyr181) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
western blot
Anti-MAPK14 (Ab-182) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Anti-phospho-MAPK14 (pThr180) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-phospho-MAPK14 (pTyr182) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-phospho-p38α (Thr180/Tyr182) Antibody, Upstate®, from rabbit,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Inhibitor
Proteins
Numer produktu
Opis
Gatunek
p38α/SAPK2a Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant, full length p38α/SAPK2a, for use in Kinase Assays.,
Gatunek
human
p38α, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human
p38α/SAPK2a (T106M) Protein, active, 10 µg, Active, N-terminal GST-tagged, recombinant, human, full-length p38α/SAPK2a containing the mutation T106M. Activated using DD-MKK6 & repurified using glutathione-agarose. For use in Kinase Assays.,
Gatunek
human